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Diana Machado
Diana Machado
Laboratório de Micobacterias, Unidade de Microbiologia Médica, Instituto de Higiene e Medicina
Dirección de correo verificada de ihmt.unl.pt - Página principal
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Contribution of Efflux to the Emergence of Isoniazid and Multidrug Resistance in Mycobacterium tuberculosis
D Machado, I Couto, J Perdigao, L Rodrigues, I Portugal, P Baptista, ...
PloS one 7 (4), e34538, 2012
2932012
Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs
JE Phelan, DM O’sullivan, D Machado, J Ramos, YEA Oppong, ...
Genome medicine 11, 1-7, 2019
2822019
Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex
L Rodrigues, D Machado, I Couto, L Amaral, M Viveiros
Infection, Genetics and Evolution 12 (4), 695-700, 2012
1732012
High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations
D Machado, J Perdigao, J Ramos, I Couto, I Portugal, C Ritter, ...
Journal of Antimicrobial Chemotherapy 68 (8), 1728-1732, 2013
1552013
Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus
SS Costa, C Falcão, M Viveiros, D Machado, M Martins, J Melo-Cristino, ...
BMC microbiology 11, 1-12, 2011
1272011
Inhibitors of mycobacterial efflux pumps as potential boosters for anti-tubercular drugs
M Viveiros, M Martins, L Rodrigues, D Machado, I Couto, J Ainsa, ...
Expert review of anti-infective therapy 10 (9), 983-998, 2012
1262012
Revisiting susceptibility testing in MDR-TB by a standardized quantitative phenotypic assessment in a European multicentre study
E Cambau, M Viveiros, D Machado, L Raskine, C Ritter, E Tortoli, ...
Journal of Antimicrobial Chemotherapy 70 (3), 686-696, 2015
1252015
Au-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis
B Veigas, D Machado, J Perdigao, I Portugal, I Couto, M Viveiros, ...
Nanotechnology 21 (41), 415101, 2010
1032010
Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil
T Coelho, D Machado, I Couto, R Maschmann, D Ramos, A von Groll, ...
Frontiers in Microbiology 6, 137735, 2015
1022015
Challenging the drug-likeness dogma for new drug discovery in tuberculosis
D Machado, M Girardini, M Viveiros, M Pieroni
Frontiers in microbiology 9, 383242, 2018
1002018
Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis
D Machado, D Pires, J Perdigao, I Couto, I Portugal, M Martins, L Amaral, ...
PloS one 11 (2), e0149326, 2016
972016
Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis
D Machado, TS Coelho, J Perdigao, C Pereira, I Couto, I Portugal, ...
Frontiers in microbiology 8, 711, 2017
872017
Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex isolates–the EUCAST broth microdilution reference method for MIC determination
T Schön, J Werngren, D Machado, E Borroni, M Wijkander, G Lina, ...
Clinical Microbiology and Infection 26 (11), 1488-1492, 2020
842020
Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting
J Perdigão, H Silva, D Machado, R Macedo, F Maltez, C Silva, L Jordao, ...
BMC genomics 15, 1-20, 2014
812014
Geographic distribution of nontuberculous mycobacteria isolated from clinical specimens: a systematic review
SMH Zweijpfenning, J van Ingen, W Hoefsloot
Seminars in respiratory and critical care medicine 39 (03), 336-342, 2018
792018
The role of efflux pumps in macrolide resistance in Mycobacterium avium complex
L Rodrigues, D Sampaio, I Couto, D Machado, WV Kern, L Amaral, ...
International journal of antimicrobial agents 34 (6), 529-533, 2009
792009
Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery
E Azzali, D Machado, A Kaushik, F Vacondio, S Flisi, CS Cabassi, ...
Journal of medicinal chemistry 60 (16), 7108-7122, 2017
762017
HIV and tuberculosis co-infection among migrants in Europe: A systematic review on the prevalence, incidence and mortality
AM Tavares, I Fronteira, I Couto, D Machado, M Viveiros, AB Abecasis, ...
PloS one 12 (9), e0185526, 2017
742017
The membrane periodic skeleton is an actomyosin network that regulates axonal diameter and conduction
AR Costa, SC Sousa, R Pinto-Costa, JC Mateus, CDF Lopes, AC Costa, ...
Elife 9, e55471, 2020
652020
Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs. Genome Med 11: 41
JE Phelan, DM O’sullivan, D Machado, J Ramos, YEA Oppong, ...
DOI: https://doi. org/10.1186/s13073-019-0650-x. PMID: https://www. ncbi …, 2019
652019
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