Michael T. Lewis
Michael T. Lewis
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Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy
X Li, MT Lewis, J Huang, C Gutierrez, CK Osborne, MF Wu, ...
Journal of the National Cancer Institute 100 (9), 672-679, 2008
Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features
CJ Creighton, X Li, M Landis, JM Dixon, VM Neumeister, A Sjolund, ...
Proceedings of the National Academy of Sciences 106 (33), 13820-13825, 2009
Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
L Tian, A Goldstein, H Wang, H Ching Lo, IK Sun Kim, T Welte, K Sheng, ...
Nature 544 (7649), 250-254, 2017
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models
X Zhang, S Claerhout, A Prat, LE Dobrolecki, I Petrovic, Q Lai, MD Landis, ...
Cancer research 73 (15), 4885-4897, 2013
Patient-derived xenograft models of breast cancer and their predictive power
JR Whittle, MT Lewis, GJ Lindeman, JE Visvader
Breast cancer research 17, 1-13, 2015
Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an …
HJ Kim, BC Litzenburger, X Cui, DA Delgado, BC Grabiner, X Lin, ...
Molecular and cellular biology 27 (8), 3165-3175, 2007
Fatty acid oxidation-driven Src links mitochondrial energy reprogramming and oncogenic properties in triple-negative breast cancer
JH Park, S Vithayathil, S Kumar, PL Sung, LE Dobrolecki, V Putluri, ...
Cell reports 14 (9), 2154-2165, 2016
Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors
AF Schott, MD Landis, G Dontu, KA Griffith, RM Layman, I Krop, ...
Clinical Cancer Research 19 (6), 1512-1524, 2013
Patient-derived xenograft (PDX) models in basic and translational breast cancer research
LE Dobrolecki, SD Airhart, DG Alferez, S Aparicio, F Behbod, ...
Cancer and Metastasis Reviews 35, 547-573, 2016
A region of proto-dbl essential for its transforming activity shows sequence similarity to a yeast cell cycle gene, CDC24, and the human breakpoint cluster gene, bcr.
D Ron, M Zannini, M Lewis, RB Wickner, LT Hunt, G Graziani, SR Tronick, ...
The New Biologist 3 (4), 372-379, 1991
Patterns of resistance and incomplete response to docetaxel by gene expression profiling in breast cancer patients
JC Chang, EC Wooten, A Tsimelzon, SG Hilsenbeck, MC Gutierrez, ...
Journal of Clinical Oncology 23 (6), 1169-1177, 2005
Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells
F De Amicis, J Thirugnansampanthan, Y Cui, J Selever, A Beyer, I Parra, ...
Breast cancer research and treatment 121, 1-11, 2010
Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia
RC Moraes, X Zhang, N Harrington, JY Fung, MF Wu, SG Hilsenbeck, ...
Oxford University Press for The Company of Biologists Limited 134 (6), 1231-1242, 2007
Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells
AH Klopp, L Lacerda, A Gupta, BG Debeb, T Solley, L Li, E Spaeth, W Xu, ...
PloS one 5 (8), e12180, 2010
Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation
T Welte, IS Kim, L Tian, X Gao, H Wang, J Li, XB Holdman, ...
Nature cell biology 18 (6), 632-644, 2016
Membrane-localized estrogen receptor α is required for normal organ development and function
A Pedram, M Razandi, M Lewis, S Hammes, ER Levin
Developmental cell 29 (4), 482-490, 2014
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer
NA Zhao, J Cao, L Xu, Q Tang, LE Dobrolecki, X Lv, M Talukdar, Y Lu, ...
The Journal of clinical investigation 128 (4), 1283-1299, 2018
The terminal end bud: the little engine that could
IS Paine, MT Lewis
Journal of mammary gland biology and neoplasia 22, 93-108, 2017
A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology
KP Guillen, M Fujita, AJ Butterfield, SD Scherer, MH Bailey, Z Chu, ...
Nature cancer 3 (2), 232-250, 2022
Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1
MT Lewis, S Ross, PA Strickland, CW Sugnet, E Jimenez, MP Scott, ...
Development 126 (22), 5181-5193, 1999
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