Kristina Kirschner
Kristina Kirschner
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SC3: consensus clustering of single-cell RNA-seq data
VY Kiselev, K Kirschner, MT Schaub, T Andrews, A Yiu, T Chandra, ...
Nature methods 14 (5), 483-486, 2017
Autophagy mediates the mitotic senescence transition
ARJ Young, M Narita, M Ferreira, K Kirschner, M Sadaie, JFJ Darot, ...
Genes & development 23 (7), 798-803, 2009
Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis
S Alivernini, L MacDonald, A Elmesmari, S Finlay, B Tolusso, MR Gigante, ...
Nature medicine 26 (8), 1295-1306, 2020
Global reorganization of the nuclear landscape in senescent cells
T Chandra, PA Ewels, S Schoenfelder, M Furlan-Magaril, SW Wingett, ...
Cell reports 10 (4), 471-483, 2015
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation
T Chandra, K Kirschner, JY Thuret, BD Pope, T Ryba, S Newman, ...
Molecular cell 47 (2), 203-214, 2012
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress
R Burt, A Dey, S Aref, M Aguiar, A Akarca, K Bailey, W Day, S Hooper, ...
Blood, The Journal of the American Society of Hematology 134 (17), 1415-1429, 2019
NOTUM from Apc-mutant cells biases clonal competition to initiate cancer
DJ Flanagan, N Pentinmikko, K Luopajärvi, NJ Willis, K Gilroy, AP Raven, ...
Nature 594 (7863), 430-435, 2021
Multiple roles of the ERCC1-XPF endonuclease in DNA repair and resistance to anticancer drugs
K Kirschner, DW Melton
Anticancer research 30 (9), 3223-3232, 2010
Experimental design for single-cell RNA sequencing
J Baran-Gale, T Chandra, K Kirschner
Briefings in functional genomics 17 (4), 233-239, 2018
Amplification of HSD17B1 and ERBB2 in primary breast cancer
C Gunnarsson, M Ahnström, K Kirschner, B Olsson, B Nordenskjöld, ...
Oncogene 22 (1), 34-40, 2003
Notch signaling mediates secondary senescence
YV Teo, N Rattanavirotkul, N Olova, A Salzano, A Quintanilla, N Tarrats, ...
Cell reports 27 (4), 997-1007. e5, 2019
Proliferation drives aging-related functional decline in a subpopulation of the hematopoietic stem cell compartment
K Kirschner, T Chandra, V Kiselev, D Flores-Santa Cruz, IC Macaulay, ...
Cell reports 19 (8), 1503-1511, 2017
Cytokine‐induced megakaryocytic differentiation is regulated by genome‐wide loss of a uSTAT transcriptional program
HJ Park, J Li, R Hannah, S Biddie, AI Leal‐Cervantes, K Kirschner, ...
The EMBO journal 35 (6), 580-594, 2016
Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion
DG Kent, J Li, H Tanna, J Fink, K Kirschner, DC Pask, Y Silber, ...
PLoS biology 11 (6), e1001576, 2013
Improving outcomes in chronic myeloid leukemia through harnessing the immunological landscape
YC Hsieh, K Kirschner, M Copland
Leukemia 35 (5), 1229-1242, 2021
Latent regulatory potential of human-specific repetitive elements
MC Ward, MD Wilson, NL Barbosa-Morais, D Schmidt, R Stark, Q Pan, ...
Molecular cell 49 (2), 262-272, 2013
Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism for Chronically Activated p53
Plos Genetics, 2015
Longitudinal dynamics of clonal hematopoiesis identifies gene-specific fitness effects
NA Robertson, E Latorre-Crespo, M Terradas-Terradas, J Lemos-Portela, ...
Nature medicine 28 (7), 1439-1446, 2022
Multi-layered spatial transcriptomics identify secretory factors promoting human hematopoietic stem cell development
EI Crosse, S Gordon-Keylock, S Rybtsov, A Binagui-Casas, H Felchle, ...
Cell Stem Cell 27 (5), 822-839. e8, 2020
Functional heterogeneity in senescence
K Kirschner, N Rattanavirotkul, MF Quince, T Chandra
Biochemical Society Transactions 48 (3), 765-773, 2020
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