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Thomas W Burke
Thomas W Burke
Duke Center for Applied Genomics & Precision Medicine
Dirección de correo verificada de duke.edu
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The downstream core promoter element, DPE, is conserved fromDrosophila to humans and is recognized by TAFII60 of Drosophila
TW Burke, JT Kadonaga
Genes & development 11 (22), 3020-3031, 1997
7321997
Drosophila TFIID binds to a conserved downstream basal promoter element that is present in many TATA-box-deficient promoters.
TW Burke, JT Kadonaga
Genes & development 10 (6), 711-724, 1996
6641996
Host gene expression classifiers diagnose acute respiratory illness etiology
EL Tsalik, R Henao, M Nichols, T Burke, ER Ko, MT McClain, LL Hudson, ...
Science translational medicine 8 (322), 322ra11-322ra11, 2016
2592016
Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1
TW Burke, JG Cook, M Asano, JR Nevins
Journal of Biological Chemistry 276 (18), 15397-15408, 2001
2542001
Analysis of Cdc6 function in the assembly of mammalian prereplication complexes
JG Cook, CH Park, TW Burke, G Leone, J DeGregori, A Engel, JR Nevins
Proceedings of the National Academy of Sciences 99 (3), 1347-1352, 2002
1542002
A host-based RT-PCR gene expression signature to identify acute respiratory viral infection
AK Zaas, T Burke, M Chen, M McClain, B Nicholson, T Veldman, EL Tsalik, ...
Science translational medicine 5 (203), 203ra126-203ra126, 2013
1432013
Severe acute respiratory syndrome coronavirus 2 viremia is associated with coronavirus disease 2019 severity and predicts clinical outcomes
JL Jacobs, W Bain, A Naqvi, B Staines, PMS Castanha, H Yang, VF Boltz, ...
Clinical Infectious Diseases 74 (9), 1525-1533, 2022
128*2022
The DPE, a conserved downstream core promoter element that is functionally analogous to the TATA box
TW Burke, PJ Willy, AK Kutach, JEF Butler, JT Kadonaga
Cold Spring Harbor symposia on quantitative biology 63, 75-82, 1998
1021998
Sp1 activation of a TATA-less promoter requires a species-specific interaction involving transcription factor IID
KH Emami, ST Smale, TW Burke
Nucleic acids research 26 (3), 839-846, 1998
961998
Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
MT McClain, FJ Constantine, R Henao, Y Liu, EL Tsalik, TW Burke, ...
Nature communications 12 (1), 1079, 2021
842021
Centralized biorepositories for genetic and genomic research
GS Ginsburg, TW Burke, P Febbo
Jama 299 (11), 1359-1361, 2008
802008
An individualized predictor of health and disease using paired reference and target samples
TY Liu, T Burke, LP Park, CW Woods, AK Zaas, GS Ginsburg, AO Hero
BMC bioinformatics 17, 1-15, 2016
702016
The current epidemiology and clinical decisions surrounding acute respiratory infections
AK Zaas, BH Garner, EL Tsalik, T Burke, CW Woods, GS Ginsburg
Trends in molecular medicine 20 (10), 579-588, 2014
692014
Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip
HT Ngo, HN Wang, T Burke, GS Ginsburg, T Vo-Dinh
Analytical and bioanalytical chemistry 406, 3335-3344, 2014
682014
An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
L Wang, TJ Balmat, AL Antonia, FJ Constantine, R Henao, TW Burke, ...
Genome medicine 13 (1), 83, 2021
592021
Asymptomatic or mild symptomatic SARS-CoV-2 infection elicits durable neutralizing antibody responses in children and adolescents
C Garrido, JH Hurst, CG Lorang, JN Aquino, J Rodriguez, TS Pfeiffer, ...
JCI Insight 6 (17), e150909, 2021
542021
Validation of a host response test to distinguish bacterial and viral respiratory infection
EC Lydon, R Henao, TW Burke, M Aydin, BP Nicholson, SW Glickman, ...
EBioMedicine 48, 453-461, 2019
512019
Comparing reference-based RNA-Seq mapping methods for non-human primate data
AM Benjamin, M Nichols, TW Burke, GS Ginsburg, JE Lucas
BMC genomics 15, 1-14, 2014
502014
Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test
JT Heggestad, DS Kinnamon, LB Olson, J Liu, G Kelly, SA Wall, ...
Science advances 7 (26), eabg4901, 2021
492021
Discriminating bacterial and viral infection using a rapid host gene expression test
EL Tsalik, R Henao, JL Montgomery, JW Nawrocki, M Aydin, EC Lydon, ...
Critical care medicine 49 (10), 1651-1663, 2021
482021
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