An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma P Sumazin, X Yang, HS Chiu, WJ Chung, A Iyer, D Llobet-Navas, ... Cell 147 (2), 370-381, 2011 | 795 | 2011 |
Elucidating compound mechanism of action by network perturbation analysis JH Woo, Y Shimoni, WS Yang, P Subramaniam, A Iyer, P Nicoletti, ... Cell 162 (2), 441-451, 2015 | 366 | 2015 |
Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks JC Chen, MJ Alvarez, F Talos, H Dhruv, GE Rieckhof, A Iyer, KL Diefes, ... Cell 159 (2), 402-414, 2014 | 214 | 2014 |
Cross-cohort analysis identifies a TEAD4–MYCN positive feedback loop as the core regulatory element of high-risk neuroblastoma P Rajbhandari, G Lopez, C Capdevila, B Salvatori, J Yu, ... Cancer discovery 8 (5), 582-599, 2018 | 148 | 2018 |
HLA-independent T cell receptors for targeting tumors with low antigen density J Mansilla-Soto, J Eyquem, S Haubner, M Hamieh, J Feucht, N Paillon, ... Nature medicine 28 (2), 345-352, 2022 | 129 | 2022 |
Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks HS Chiu, D Llobet-Navas, X Yang, WJ Chung, A Ambesi-Impiombato, ... Genome research 25 (2), 257-267, 2015 | 109 | 2015 |
Regulation of CXC chemokine receptor 4-mediated migration by the Tec family tyrosine kinase ITK AM Fischer, JC Mercer, A Iyer, MJ Ragin, A August Journal of Biological Chemistry 279 (28), 29816-29820, 2004 | 109 | 2004 |
Enhanced development of CD4+ γδ T cells in the absence of Itk results in elevated IgE production Q Qi, M Xia, J Hu, E Hicks, A Iyer, N Xiong, A August Blood, The Journal of the American Society of Hematology 114 (3), 564-571, 2009 | 107 | 2009 |
miR-182 regulates Slit2-mediated axon guidance by modulating the local translation of a specific mRNA A Bellon, A Iyer, S Bridi, FCY Lee, C Ovando-Vazquez, E Corradi, ... Cell reports 18 (5), 1171-1186, 2017 | 99 | 2017 |
Axonal precursor mi RNA s hitchhike on endosomes and locally regulate the development of neural circuits E Corradi, I Dalla Costa, A Gavoci, A Iyer, M Roccuzzo, TA Otto, E Oliani, ... The EMBO journal 39 (6), e102513, 2020 | 78 | 2020 |
TET2 guards against unchecked BATF3-induced CAR T cell expansion N Jain, Z Zhao, J Feucht, R Koche, A Iyer, A Dobrin, J Mansilla-Soto, ... Nature 615 (7951), 315-322, 2023 | 68 | 2023 |
microRNAs in axon guidance AN Iyer, A Bellon, ML Baudet Frontiers in cellular neuroscience 8, 78, 2014 | 63 | 2014 |
Absence of Tec family kinases interleukin-2 inducible T cell kinase (Itk) and Bruton's tyrosine kinase (Btk) severely impairs FcϵRI-dependent mast cell responses AS Iyer, JL Morales, W Huang, F Ojo, G Ning, E Wills, JD Baines, ... Journal of Biological Chemistry 286 (11), 9503-9513, 2011 | 58 | 2011 |
A new mitochondrial pool of cyclin E, regulated by Drp1, is linked to cell-density-dependent cell proliferation DJ Parker, A Iyer, S Shah, A Moran, AB Hjelmeland, MK Basu, R Liu, ... Journal of cell science 128 (22), 4171-4182, 2015 | 49 | 2015 |
Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2 M Law, JL Morales, LF Mottram, A Iyer, BR Peterson, A August The international journal of biochemistry & cell biology 43 (8), 1228-1239, 2011 | 46 | 2011 |
Chemico-genetic identification of drebrin as a regulator of calcium responses JC Mercer, Q Qi, LF Mottram, M Law, D Bruce, A Iyer, JL Morales, ... The international journal of biochemistry & cell biology 42 (2), 337-345, 2010 | 45 | 2010 |
The Tec family kinase, IL-2-inducible T cell kinase, differentially controls mast cell responses AS Iyer, A August The Journal of Immunology 180 (12), 7869-7877, 2008 | 40 | 2008 |
Neuronal diversity and reciprocal connectivity between the vertebrate hippocampus and septum A Iyer, S Tole Wiley Interdisciplinary Reviews: Developmental Biology 9 (4), e370, 2020 | 24 | 2020 |
Computational methods to dissect gene regulatory networks in cancer AS Iyer, HU Osmanbeyoglu, CS Leslie Current opinion in systems biology 2, 115-122, 2017 | 16 | 2017 |
Amine oxidation by d-arginine dehydrogenase in Pseudomonas aeruginosa D Ouedraogo, J Ball, A Iyer, RAG Reis, M Vodovoz, G Gadda Archives of Biochemistry and Biophysics 632, 192-201, 2017 | 14 | 2017 |