Dave Sprengers
Dave Sprengers
Dept Gastroenterology and Hepatology, Erasmus MC University Hospital Rotterdam, The Netherlands
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Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B
RG van der Molen, D Sprengers, RS Binda, EC de Jong, HGM Niesters, ...
Hepatology 40 (3), 738-746, 2004
Antibodies against immune checkpoint molecules restore functions of tumor-infiltrating T cells in hepatocellular carcinomas
G Zhou, D Sprengers, PPC Boor, M Doukas, H Schutz, S Mancham, ...
Gastroenterology 153 (4), 1107-1119. e10, 2017
Lactobacillus GG prevents recurrence of colitis in HLA-B27 transgenic rats after antibiotic treatment
LA Dieleman, MS Goerres, A Arends, D Sprengers, C Torrice, F Hoentjen, ...
Gut 52 (3), 370-376, 2003
Activated tumor‐infiltrating CD4+ regulatory T cells restrain antitumor immunity in patients with primary or metastatic liver cancer
A Pedroza‐Gonzalez, C Verhoef, JNM Ijzermans, MP Peppelenbosch, ...
Hepatology 57 (1), 183-194, 2013
Modeling rotavirus infection and antiviral therapy using primary intestinal organoids
Y Yin, M Bijvelds, W Dang, L Xu, AA van der Eijk, K Knipping, N Tuysuz, ...
Antiviral research 123, 120-131, 2015
Surveillance for hepatocellular carcinoma is associated with increased survival: results from a large cohort in the Netherlands
S van Meer, RA de Man, MJ Coenraad, D Sprengers, KMJ van Nieuwkerk, ...
Journal of hepatology 63 (5), 1156-1163, 2015
TIGIT, the next step towards successful combination immune checkpoint therapy in cancer
Z Ge, MP Peppelenbosch, D Sprengers, J Kwekkeboom
Frontiers in immunology 12, 699895, 2021
Flares in chronic hepatitis B patients induced by the host or the virus? Relation to treatment response during Peg-interferon α-2b therapy
HJ Flink, D Sprengers, BE Hansen, M van Zonneveld, RA De Man, ...
Gut 54 (11), 1604-1609, 2005
PD-L1, Galectin-9 and CD8+ tumor-infiltrating lymphocytes are associated with survival in hepatocellular carcinoma
K Sideras, K Biermann, J Verheij, BR Takkenberg, S Mancham, ...
Oncoimmunology 6 (2), e1273309, 2017
Cancer-associated fibroblasts provide a stromal niche for liver cancer organoids that confers trophic effects and therapy resistance
J Liu, P Li, L Wang, M Li, Z Ge, L Noordam, R Lieshout, MMA Verstegen, ...
Cellular and molecular gastroenterology and hepatology 11 (2), 407-431, 2021
Hepatitis E virus infects neurons and brains
X Zhou, F Huang, L Xu, Z Lin, FMS de Vrij, AC Ayo-Martin, ...
The Journal of infectious diseases 215 (8), 1197-1206, 2017
Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors
A Pedroza-Gonzalez, G Zhou, E Vargas-Mendez, PPC Boor, S Mancham, ...
Oncoimmunology 4 (6), e1008355, 2015
Reduction of immunosuppressive tumor microenvironment in cholangiocarcinoma by ex vivo targeting immune checkpoint molecules
G Zhou, D Sprengers, S Mancham, R Erkens, PPC Boor, AA van Beek, ...
Journal of hepatology 71 (4), 753-762, 2019
α-Galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial
AM Woltman, MJ Ter Borg, RS Binda, D Sprengers, BME von Blomberg, ...
Antiviral therapy 14 (6), 809-818, 2009
Favorable effect of adefovir on the number and functionality of myeloid dendritic cells of patients with chronic HBV
RG van der Molen, D Sprengers, PJ Biesta, JG Kusters, HLA Janssen
Hepatology 44 (4), 907-914, 2006
Bleeding time in patients with hepatic cirrhosis.
JC Blake, D Sprengers, P Grech, PA McCormick, N McIntyre, ...
British Medical Journal 301 (6742), 12-15, 1990
Multiple biopsy passes and the risk of complications of percutaneous liver biopsy
H Chi, BE Hansen, WY Tang, JNL Schouten, D Sprengers, P Taimr, ...
European journal of gastroenterology & hepatology 29 (1), 36-41, 2017
Mitochondrial fusion via OPA1 and MFN1 supports liver tumor cell metabolism and growth
M Li, L Wang, Y Wang, S Zhang, G Zhou, R Lieshout, B Ma, J Liu, C Qu, ...
Cells 9 (1), 121, 2020
Cross talk between nucleotide synthesis pathways with cellular immunity in constraining hepatitis E virus replication
Y Wang, W Wang, L Xu, X Zhou, E Shokrollahi, K Felczak, ...
Antimicrobial agents and chemotherapy 60 (5), 2834-2848, 2016
Different composition of intrahepatic lymphocytes in the immune‐tolerance and immune‐clearance phase of chronic hepatitis B
D Sprengers, RG Van der Molen, JG Kusters, B Hansen, HGM Niesters, ...
Journal of medical virology 78 (5), 561-568, 2006
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