Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection J Wei, MM Alfajaro, PC DeWeirdt, RE Hanna, WJ Lu-Culligan, WL Cai, ... Cell 184 (1), 76-91. e13, 2021 | 502* | 2021 |
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling B Israelow, E Song, T Mao, P Lu, A Meir, F Liu, MM Alfajaro, J Wei, ... Journal of Experimental Medicine 217 (12), e20201241, 2020 | 405 | 2020 |
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes NG Ravindra, MM Alfajaro, V Gasque, NC Huston, H Wan, K Szigeti-Buck, ... PLoS biology 19 (3), e3001143, 2021 | 264* | 2021 |
Nonsteroidal anti-inflammatory drugs dampen the cytokine and antibody response to SARS-CoV-2 infection JS Chen, MM Alfajaro, RD Chow, J Wei, RB Filler, SC Eisenbarth, ... Journal of virology 95 (7), 10.1128/jvi. 00014-21, 2021 | 170* | 2021 |
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions RA Flynn, JA Belk, Y Qi, Y Yasumoto, J Wei, MM Alfajaro, Q Shi, ... Cell 184 (9), 2394-2411. e16, 2021 | 139 | 2021 |
ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response H Lian, J Wei, R Zang, W Ye, Q Yang, XN Zhang, YD Chen, YZ Fu, MM Hu, ... Nature communications 9 (1), 3349, 2018 | 110 | 2018 |
TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses Q Yang, TT Liu, H Lin, M Zhang, J Wei, WW Luo, YH Hu, B Zhong, MM Hu, ... PLoS pathogens 13 (9), e1006600, 2017 | 107 | 2017 |
The zinc-finger protein ZCCHC3 binds RNA and facilitates viral RNA sensing and activation of the RIG-I-like receptors H Lian, R Zang, J Wei, W Ye, MM Hu, YD Chen, XN Zhang, Y Guo, CQ Lei, ... Immunity 49 (3), 438-448. e5, 2018 | 104 | 2018 |
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection SB Biering, SA Sarnik, E Wang, JR Zengel, SR Leist, A Schäfer, ... Nature genetics 54 (8), 1078-1089, 2022 | 85* | 2022 |
Transmembrane Protein 214 (TMEM214) mediates endoplasmic reticulum stress-induced caspase 4 enzyme activation and apoptosis C Li, J Wei, Y Li, X He, Q Zhou, J Yan, J Zhang, Y Liu, Y Liu, HB Shu Journal of Biological Chemistry 288 (24), 17908-17917, 2013 | 69 | 2013 |
CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus VR Graziano, FC Walker, EA Kennedy, J Wei, K Ettayebi, MS Strine, ... PLoS pathogens 16 (4), e1008242, 2020 | 59 | 2020 |
Norovirus attachment and entry VR Graziano, J Wei, CB Wilen Viruses 11 (6), 495, 2019 | 58 | 2019 |
Foot-and-mouth disease virus structural protein VP3 degrades Janus kinase 1 to inhibit IFN-γ signal transduction pathways D Li, J Wei, F Yang, HN Liu, ZX Zhu, WJ Cao, S Li, XT Liu, HX Zheng, ... Cell cycle 15 (6), 850-860, 2016 | 49 | 2016 |
RAVER1 is a coactivator of MDA5-mediated cellular antiviral response H Chen, Y Li, J Zhang, Y Ran, J Wei, Y Yang, HB Shu Journal of molecular cell biology 5 (2), 111-119, 2013 | 39 | 2013 |
High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells JS Chen, RD Chow, E Song, T Mao, B Israelow, K Kamath, J Bozekowski, ... Science immunology 7 (68), eabl5652, 2021 | 37* | 2021 |
MARCH3 attenuates IL-1β–triggered inflammation by mediating K48-linked polyubiquitination and degradation of IL-1RI H Lin, D Gao, MM Hu, M Zhang, XX Wu, L Feng, WH Xu, Q Yang, X Zhong, ... Proceedings of the National Academy of Sciences 115 (49), 12483-12488, 2018 | 36 | 2018 |
SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA J Wei, H Lian, W Guo, YD Chen, XN Zhang, R Zang, L Zhong, Q Yang, ... PLoS Pathogens 14 (10), e1007336, 2018 | 34 | 2018 |
SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes J Wei, W Guo, H Lian, Q Yang, H Lin, S Li, HB Shu Proceedings of the National Academy of Sciences 114 (49), 13000-13005, 2017 | 25 | 2017 |
CD300lf conditional knockout mouse reveals strain-specific cellular tropism of murine norovirus VR Graziano, MM Alfajaro, CO Schmitz, RB Filler, MS Strine, J Wei, ... Journal of virology 95 (3), 10.1128/jvi. 01652-20, 2021 | 24 | 2021 |
SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA W Guo, J Wei, X Zhong, R Zang, H Lian, MM Hu, S Li, HB Shu, Q Yang Cellular & molecular immunology 17 (11), 1126-1135, 2020 | 22 | 2020 |