Professor David Jane
Professor David Jane
Professor of Chemical Pharmacology, University of Bristol
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Pharmacological agents acting at subtypes of metabotropic glutamate receptors
DD Schoepp, DE Jane, JA Monn
Neuropharmacology 38 (10), 1431-1476, 1999
Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors
ZI Bashir, ZA Bortolotto, CH Davies, N Berretta, AJ Irving, AJ Seal, ...
Nature 363 (6427), 347-350, 1993
The glutamate story
JC Watkins, DE Jane
British journal of pharmacology 147 (S1), S100-S108, 2006
The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus
MJ Palmer, AJ Irving, GR Seabrook, DE Jane, GL Collingridge
Neuropharmacology 36 (11-12), 1517-1532, 1997
Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes
Y Hayashi, N Sekiyama, S Nakanishi, DE Jane, DC Sunter, EF Birse, ...
Journal of Neuroscience 14 (5), 3370-3377, 1994
-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but not mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus
AJ Doherty, MJ Palmer, JM Henley, GL Collingridge, DE Jane
Neuropharmacology 36 (2), 265-267, 1997
Kainate receptors: pharmacology, function and therapeutic potential
DE Jane, D Lodge, GL Collingridge
Neuropharmacology 56 (1), 90-113, 2009
The NMDA receptor as a target for cognitive enhancement
GL Collingridge, A Volianskis, N Bannister, G France, L Hanna, M Mercier, ...
Neuropharmacology 64, 13-26, 2013
Long-term potentiation and the role of N-methyl-D-aspartate receptors
A Volianskis, G France, MS Jensen, ZA Bortolotto, DE Jane, ...
Brain research 1621, 5-16, 2015
Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-α-methyl-4-carboxyphenylglycine
SA Eaton, DE Jane, PLSJ Jones, RHP Porter, PCK Pook, DC Sunter, ...
European Journal of Pharmacology: Molecular Pharmacology 244 (2), 195-197, 1993
Actions of two new antagonists showing selectivity for different sub‐types of metabotropic glutamate receptor in the neonatal rat spinal cord
DE Jane, PLSJ Jones, PCK Pook, HW Tse, JC Watkins
British journal of pharmacology 112 (3), 809-816, 1994
Synthesis of simple oxetanes carrying reactive 2-substituents
AO Fitton, J Hill, DE Jane, R Millar
Synthesis 1987 (12), 1140-1142, 1987
Distinct NMDA receptor subpopulations contribute to long-term potentiation and long-term depression induction
S Hrabetova, P Serrano, N Blace, WT Heong, DA Skifter, DE Jane, ...
The Journal of Neuroscience 20 (12), RC81, 2000
Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus
ZI Bashir, DE Jane, DC Sunter, JC Watkins, GL Collingridge
European journal of pharmacology 239 (1-3), 265-266, 1993
Structure–activity analysis of a novel NR2C/NR2D‐preferring NMDA receptor antagonist: 1‐(phenanthrene‐2‐carbonyl) piperazine‐2, 3‐dicarboxylic acid
B Feng, HW Tse, DA Skifter, R Morley, DE Jane, DT Monaghan
British journal of pharmacology 141 (3), 508-516, 2004
Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system
EF Birse, SA Eaton, DE Jane, PLSJ Jones, RHP Porter, PCK Pook, ...
Neuroscience 52 (3), 481-488, 1993
(S)-3, 4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord
NK Thomas, RA Wright, PA Howson, AE Kingston, DD Schoepp, DE Jane
Neuropharmacology 40 (3), 311-318, 2001
Extrasynaptic NR2D-containing NMDARs are recruited to the synapse during LTP of NMDAR-EPSCs
SC Harney, DE Jane, R Anwyl
Journal of Neuroscience 28 (45), 11685-11694, 2008
NMDA receptor-dependent long-term potentiation comprises a family of temporally overlapping forms of synaptic plasticity that are induced by different patterns of stimulation
P Park, A Volianskis, TM Sanderson, ZA Bortolotto, DE Jane, M Zhuo, ...
Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014
Potent antagonists at the L-AP4-and (1S, 3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord
DE Jane, NK Thomas, HW Tse, JC Watkins
Neuropharmacology 35 (8), 1029-1035, 1996
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