PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer J Li, C Yen, D Liaw, K Podsypanina, S Bose, SI Wang, J Puc, C Miliaresis, ... science 275 (5308), 1943-1947, 1997 | 7264 | 1997 |
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems K Podsypanina, LH Ellenson, A Nemes, J Gu, M Tamura, KM Yamada, ... Proceedings of the National Academy of Sciences 96 (4), 1563, 1999 | 1225 | 1999 |
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/− mice K Podsypanina, RT Lee, C Politis, I Hennessy, A Crane, J Puc, M Neshat, ... Proceedings of the National Academy of Sciences 98 (18), 10320, 2001 | 752 | 2001 |
Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells Y Li, B Welm, K Podsypanina, S Huang, M Chamorro, X Zhang, ... Proceedings of the National Academy of Sciences 100 (26), 15853, 2003 | 672 | 2003 |
The 3′-untranslated region of CaMKIIα is a cis-acting signal for the localization and translation of mRNA in dendrites M Mayford, D Baranes, K Podsypanina, ER Kandel Proceedings of the National Academy of Sciences 93 (23), 13250, 1996 | 436 | 1996 |
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression B Kwabi-Addo, D Giri, K Schmidt, K Podsypanina, R Parsons, ... Proceedings of the National Academy of Sciences 98 (20), 11563, 2001 | 432 | 2001 |
Seeding and propagation of untransformed mouse mammary cells in the lung K Podsypanina, YCN Du, M Jechlinger, LJ Beverly, D Hambardzumyan, ... Science 321 (5897), 1841, 2008 | 376 | 2008 |
Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras K Podsypanina, K Politi, LJ Beverly, HE Varmus Proceedings of the National Academy of Sciences 105 (13), 5242, 2008 | 172 | 2008 |
Tumor emergence is sensed by self-specific CD44hi memory Tregs that create a dominant tolerogenic environment for tumors in mice G Darrasse-Jèze, AS Bergot, A Durgeau, F Billiard, BL Salomon, ... The Journal of clinical investigation 119 (9), 2648-2662, 2009 | 167 | 2009 |
Introduction of oncogenes into mammary glands in vivo with an avian retroviral vector initiates and promotes carcinogenesis in mouse models Z Du, K Podsypanina, S Huang, A McGrath, MJ Toneff, E Bogoslovskaia, ... Proceedings of the National Academy of Sciences 103 (46), 17396-17401, 2006 | 119 | 2006 |
Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice Y Li, K Podsypanina, X Liu, A Crane, L Tan, R Parsons, H Varmus BMC molecular biology 2 (1), 2, 2001 | 118 | 2001 |
Differential interleukin-6/Stat3 signaling as a function of cellular context mediates Ras-induced transformation K Leslie, SP Gao, M Berishaj, K Podsypanina, H Ho, L Ivashkiv, ... Breast Cancer Res 12, R80, 2010 | 96 | 2010 |
DNA mismatch repair deficiency accelerates endometrial tumorigenesis in Pten heterozygous mice H Wang, W Douglas, M Lia, W Edelmann, R Kucherlapati, K Podsypanina, ... The American journal of pathology 160 (4), 1481, 2002 | 93 | 2002 |
Regulation of transgenes in three-dimensional cultures of primary mouse mammary cells demonstrates oncogene dependence and identifies cells that survive deinduction M Jechlinger, K Podsypanina, H Varmus Genes & development 23 (14), 1677-1688, 2009 | 83 | 2009 |
Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations X Zhang, K Podsypanina, S Huang, SK Mohsin, GC Chamness, S Hatsell, ... Oncogene 24 (26), 4220-4231, 2005 | 73 | 2005 |
Essential role for centromeric factors following p53 loss and oncogenic transformation D Filipescu, M Naughtin, K Podsypanina, V Lejour, L Wilson, ... Genes & development 31 (5), 463-480, 2017 | 70 | 2017 |
Hyperprolactinemia-inducing antipsychotics increase breast cancer risk by activating JAK-STAT5 in precancerous lesions AN Johnston, W Bu, S Hein, S Garcia, L Camacho, L Xue, L Qin, C Nagi, ... Breast Cancer Research 20, 1-13, 2018 | 69 | 2018 |
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation JP Reddy, S Peddibhotla, W Bu, J Zhao, S Haricharan, YCN Du, ... Proceedings of the National Academy of Sciences 107 (8), 3728-3733, 2010 | 61 | 2010 |
Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype K Podsypanina, Y Li, H Varmus BMC medicine 2 (1), 24, 2004 | 59 | 2004 |
How Numbers, Nature, and Immune Status of Foxp3+ Regulatory T-Cells Shape the Early Immunological Events in Tumor Development G Darrasse-Jèze, K Podsypanina Frontiers in immunology 4, 292, 2013 | 57 | 2013 |