Emanuel Gonçalves
Emanuel Gonçalves
INESC-ID & IST - Universidade de Lisboa
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Citado por
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver, G Migliardi, ...
Nature 568 (7753), 511-516, 2019
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
M Sciacovelli, E Gonçalves, TI Johnson, VR Zecchini, ASH Da Costa, ...
Nature 537 (7621), 544-547, 2016
CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms
CDA Terfve, T Cokelaer, D Henriques, A MacNamara, E Gonçalves, ...
BMC Systems Biology 6 (1), 133, 2012
SBML Level 3: an extensible format for the exchange and reuse of biological models
SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ...
Molecular systems biology 16 (8), e9110, 2020
Integrated cross-study datasets of genetic dependencies in cancer
C Pacini, JM Dempster, I Boyle, E Gonçalves, H Najgebauer, E Karakoc, ...
Nature communications 12 (1), 1661, 2021
Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets
JM Dempster, C Pacini, S Pantel, FM Behan, T Green, J Krill-Burger, ...
Nature communications 10 (1), 5817, 2019
SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools
C Chaouiya, D Bérenguier, SM Keating, A Naldi, MP Van Iersel, ...
BMC systems biology 7, 1-15, 2013
Genomic determinants of protein abundance variation in colorectal cancer cells
TI Roumeliotis, SP Williams, E Goncalves, FZ Ghavidel, N Aben, ...
Cell Reports 20 (9), 2201–2214, 2017
Bridging the layers: towards integration of signal transduction, regulation and metabolism into mathematical models
E Gonçalves, J Bucher, A Ryll, J Niklas, K Mauch, S Klamt, M Rocha, ...
Molecular BioSystems 9 (7), 1576-1583, 2013
Widespread post-transcriptional attenuation of genomic copy-number variation in cancer
E Gonçalves, A Fragoulis, L Garcia-Alonso, T Cramer, J Saez-Rodriguez, ...
Cell systems 5 (4), 386-398. e4, 2017
Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening
G Picco, ED Chen, LG Alonso, FM Behan, E Gonçalves, G Bignell, ...
Nature communications 10 (1), 2198, 2019
Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting
F Iorio, FM Behan, E Gonçalves, SG Bhosle, E Chen, R Shepherd, ...
BMC genomics 19, 1-16, 2018
DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data
C Pacini, F Iorio, E Gonçalves, M Iskar, T Klabunde, P Bork, ...
Bioinformatics 29 (1), 132-134, 2013
Pan-cancer proteomic map of 949 human cell lines
E Gonçalves, RC Poulos, Z Cai, S Barthorpe, SS Manda, N Lucas, A Beck, ...
Cancer Cell 40 (8), 835-849. e8, 2022
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
NA Thompson, M Ranzani, L van der Weyden, V Iyer, V Offord, A Droop, ...
Nature communications 12 (1), 1302, 2021
Benchmarking substrate-based kinase activity inference using phosphoproteomic data
C Hernandez-Armenta, D Ochoa, E Gonçalves, J Saez-Rodriguez, ...
Bioinformatics 33 (12), 1845-1851, 2017
Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens
E Goncalves, A Segura-Cabrera, C Pacini, G Picco, F Behan, P Jaaks, ...
Molecular Systems Biology, 2020
Project Score database: a resource for investigating cancer cell dependencies and prioritizing therapeutic targets
L Dwane, FM Behan, E Gonçalves, H Lightfoot, W Yang, D van der Meer, ...
Nucleic Acids Research 49 (D1), D1365-D1372, 2021
Minimal genome-wide human CRISPR-Cas9 library
E Gonçalves, M Thomas, FM Behan, G Picco, C Pacini, F Allen, A Vinceti, ...
Genome biology 22, 1-14, 2021
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