The ecoresponsive genome of Daphnia pulex JK Colbourne, ME Pfrender, D Gilbert, WK Thomas, A Tucker, TH Oakley, ... Science 331 (6017), 555-561, 2011 | 1425 | 2011 |
Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast KA Geiler-Samerotte, MF Dion, BA Budnik, SM Wang, DL Hartl, ... Proceedings of the National Academy of Sciences 108 (2), 680-685, 2011 | 329 | 2011 |
Development of a comprehensive genotype-to-fitness map of adaptation-driving mutations in yeast S Venkataram, B Dunn, Y Li, A Agarwala, J Chang, ER Ebel, ... Cell 166 (6), 1585-1596. e22, 2016 | 225 | 2016 |
The details in the distributions: why and how to study phenotypic variability KA Geiler-Samerotte, CR Bauer, S Li, N Ziv, D Gresham, ML Siegal Current opinion in biotechnology 24 (4), 752-759, 2013 | 136 | 2013 |
Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects F Pangilinan, AM Molloy, JL Mills, JF Troendle, A Parle-McDermott, ... BMC medical genetics 13, 1-19, 2012 | 105 | 2012 |
Selection transforms the landscape of genetic variation interacting with Hsp90 KA Geiler-Samerotte, YO Zhu, BE Goulet, DW Hall, ML Siegal PLoS biology 14 (10), e2000465, 2016 | 94 | 2016 |
Fitness variation across subtle environmental perturbations reveals local modularity and global pleiotropy of adaptation G Kinsler, K Geiler-Samerotte, DA Petrov Elife 9, e61271, 2020 | 91 | 2020 |
Constructive neutral evolution 20 years later SA Muñoz-Gómez, G Bilolikar, JG Wideman, K Geiler-Samerotte Journal of molecular evolution 89, 172-182, 2021 | 60 | 2021 |
Decanalizing thinking on genetic canalization K Geiler-Samerotte, FMO Sartori, ML Siegal Seminars in cell & developmental biology 88, 54-66, 2019 | 43 | 2019 |
Extent and context dependence of pleiotropy revealed by high-throughput single-cell phenotyping KA Geiler-Samerotte, S Li, C Lazaris, A Taylor, N Ziv, C Ramjeawan, ... PLoS biology 18 (8), e3000836, 2020 | 37 | 2020 |
Why and how to study genetic changes with context-dependent effects Y Eguchi, G Bilolikar, K Geiler-Samerotte Current Opinion in Genetics & Development 58, 95-102, 2019 | 30 | 2019 |
Construction of a high resolution linkage disequilibrium map to evaluate common genetic variation in TP53 and neural tube defect risk in an Irish population F Pangilinan, K Geiler, J Dolle, J Troendle, DA Swanson, AM Molloy, ... American Journal of Medical Genetics Part A 146 (20), 2617-2625, 2008 | 28 | 2008 |
Extreme sensitivity of fitness to environmental conditions: Lessons from# 1BigBatch G Kinsler, K Schmidlin, D Newell, R Eder, S Apodaca, G Lam, D Petrov, ... Journal of Molecular Evolution 91 (3), 293-310, 2023 | 15 | 2023 |
Emerging frontiers in the study of molecular evolution DA Liberles, B Chang, K Geiler-Samerotte, A Goldman, J Hey, B Kaçar, ... Journal of molecular evolution 88, 211-226, 2020 | 15 | 2020 |
Challenges and potential solutions for studying the genetic and phenotypic architecture of adaptation in microbes L Brettner, WC Ho, K Schmidlin, S Apodaca, R Eder, K Geiler-Samerotte Current opinion in genetics & development 75, 101951, 2022 | 13 | 2022 |
Quantifying condition-dependent intracellular protein levels enables high-precision fitness estimates KA Geiler-Samerotte, T Hashimoto, MF Dion, BA Budnik, EM Airoldi, ... PloS one 8 (9), e75320, 2013 | 13 | 2013 |
A Δ11 desaturase gene genealogy reveals two divergent allelic classes within the European corn borer (Ostrinia nubilalis) KA Geiler, RG Harrison BMC Evolutionary Biology 10, 1-11, 2010 | 7 | 2010 |
An ultra high‐throughput, massively multiplexable, single‐cell RNA‐seq platform in yeasts L Brettner, R Eder, K Schmidlin, K Geiler‐Samerotte Yeast 41 (4), 242-255, 2024 | 6 | 2024 |
The Complete Genome Sequence of the Staphylococcus Bacteriophage Metroid A Crane, J Abaidoo, G Beltran, D Fry, C Furey, N Green, R Johal, ... G3: Genes, Genomes, Genetics 10 (9), 2975-2979, 2020 | 2 | 2020 |
Distinguishing mutants that resist drugs via different mechanisms by examining fitness tradeoffs across hundreds of fluconazole-resistant yeast strains K Schmidlin, S Apodaca, D Newell, A Sastokas, G Kinsler, ... eLife 13, 2024 | 1 | 2024 |