| The DNA crosslink‐induced S‐phase checkpoint depends on ATR–CHK1 and ATR–NBS1–FANCD2 pathways P Pichierri, F Rosselli The EMBO journal 23 (5), 1178-1187, 2004 | 290 | 2004 |
| ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery F Ammazzalorso, LM Pirzio, M Bignami, A Franchitto, P Pichierri The EMBO journal 29 (18), 3156-3169, 2010 | 187 | 2010 |
| Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle P Pichierri, A Franchitto, P Mosesso, F Palitti Molecular biology of the cell 12 (8), 2412-2421, 2001 | 166 | 2001 |
| Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle P Pichierri, F Rosselli, A Franchitto Oncogene 22 (10), 1491-1500, 2003 | 160 | 2003 |
| Bloom's syndrome protein is required for correct relocalization of RAD50/MRE11/NBS1 complex after replication fork arrest A Franchitto, P Pichierri The Journal of cell biology 157 (1), 19-30, 2002 | 149 | 2002 |
| BLM and the FANC proteins collaborate in a common pathway in response to stalled replication forks P Pichierri, A Franchitto, F Rosselli The EMBO journal 23 (15), 3154-3163, 2004 | 143 | 2004 |
| Werner syndrome helicase activity is essential in maintaining fragile site stability LM Pirzio, P Pichierri, M Bignami, A Franchitto The Journal of cell biology 180 (2), 305-314, 2008 | 137 | 2008 |
| The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase A Franchitto, P Pichierri, R Piergentili, M Crescenzi, M Bignami, F Palitti Oncogene 22 (14), 2110-2120, 2003 | 126 | 2003 |
| DNA cross-link-dependent RAD50/MRE11/NBS1 subnuclear assembly requires the Fanconi anemia C protein P Pichierri, D Averbeck, F Rosselli Human molecular genetics 11 (21), 2531-2546, 2002 | 124 | 2002 |
| Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway A Franchitto, LM Pirzio, E Prosperi, O Sapora, M Bignami, P Pichierri The Journal of cell biology 183 (2), 241-252, 2008 | 119 | 2008 |
| Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation E Malacaria, GM Pugliese, M Honda, V Marabitti, FA Aiello, M Spies, ... Nature communications 10 (1), 1412, 2019 | 96 | 2019 |
| WRNIP 1 protects stalled forks from degradation and promotes fork restart after replication stress G Leuzzi, V Marabitti, P Pichierri, A Franchitto The EMBO journal 35 (13), 1437-1451, 2016 | 96 | 2016 |
| Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function I Murfuni, G Basile, S Subramanyam, E Malacaria, M Bignami, M Spies, ... PLoS genetics 9 (10), e1003910, 2013 | 86 | 2013 |
| Small-molecule inhibitors identify the RAD52-ssDNA interaction as critical for recovery from replication stress and for survival of BRCA2 deficient cells SR Hengel, E Malacaria, L Folly da Silva Constantino, FE Bain, A Diaz, ... Elife 5, e14740, 2016 | 81 | 2016 |
| The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation C Iannascoli, V Palermo, I Murfuni, A Franchitto, P Pichierri Nucleic acids research 43 (20), 9788-9803, 2015 | 81 | 2015 |
| Werner’s syndrome cell lines are hypersensitive to camptothecin-induced chromosomal damage P Pichierri, A Franchitto, P Mosesso, F Palitti Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 456 (1 …, 2000 | 80 | 2000 |
| Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional fanconi anemia pathway M Aggarwal, T Banerjee, JA Sommers, C Iannascoli, P Pichierri, ... Cancer research 73 (17), 5497-5507, 2013 | 75 | 2013 |
| The Werner syndrome protein: linking the replication checkpoint response to genome stability P Pichierri, F Ammazzalorso, M Bignami, A Franchitto Aging (Albany NY) 3 (3), 311, 2011 | 61 | 2011 |
| The G2-phase decatenation checkpoint is defective in Werner syndrome cells A Franchitto, J Oshima, P Pichierri Cancer research 63 (12), 3289-3295, 2003 | 61 | 2003 |
| ATM pathway activation limits R-loop-associated genomic instability in Werner syndrome cells V Marabitti, G Lillo, E Malacaria, V Palermo, M Sanchez, P Pichierri, ... Nucleic acids research 47 (7), 3485-3502, 2019 | 59 | 2019 |
