Digital twins in pharmaceutical and biopharmaceutical manufacturing: a literature review Y Chen, O Yang, C Sampat, P Bhalode, R Ramachandran, M Ierapetritou Processes 8 (9), 1088, 2020 | 189 | 2020 |
Economic analysis of batch and continuous biopharmaceutical antibody production: A review O Yang, M Qadan, M Ierapetritou Journal of pharmaceutical innovation 15, 182-200, 2020 | 111 | 2020 |
Comparison between batch and continuous monoclonal antibody production and economic analysis O Yang, S Prabhu, M Ierapetritou Industrial & Engineering Chemistry Research 58 (15), 5851-5863, 2019 | 100 | 2019 |
Recent advances in integrated process analytical techniques, modeling, and control strategies to enable continuous biomanufacturing of monoclonal antibodies V Chopda, A Gyorgypal, O Yang, R Singh, R Ramachandran, H Zhang, ... Journal of Chemical Technology & Biotechnology 97 (9), 2317-2335, 2022 | 51 | 2022 |
mAb production modeling and design space evaluation including glycosylation process O Yang, M Ierapetritou Processes 9 (2), 324, 2021 | 22 | 2021 |
Dynamics of ellipsoidal tracers in swimming algal suspensions O Yang, Y Peng, Z Liu, C Tang, X Xu, X Cheng Physical Review E 94 (4), 042601, 2016 | 21 | 2016 |
Process design and comparison for batch and continuous manufacturing of recombinant adeno-associated virus O Yang, Y Tao, M Qadan, M Ierapetritou Journal of Pharmaceutical Innovation 18 (1), 275-286, 2023 | 13 | 2023 |
Digital twins in pharmaceutical and biopharmaceutical manufacturing: a literature review. Processes 8 (9): 1088 Y Chen, O Yang, C Sampat, P Bhalode, R Ramachandran, M Ierapetritou | 7 | 2020 |
Towards Digital Twin for Biopharmaceutical Processes: Concept and Progress C Ding, O Yang, M Ierapetritou Biopharmaceutical Manufacturing: Progress, Trends and Challenges, 179-211, 2024 | 5 | 2024 |
Digital twins in pharmaceutical and biopharmaceutical manufacturing: a literature review. Processes 8: 1088 Y Chen, O Yang, C Sampat, P Bhalode, R Ramachandran, M Ierapetritou | 5 | 2020 |
Digital Twins in Pharmaceutical and Biopharmaceutical Manufacturing: A Literature Review. Processes 2020, 8, 1088 Y Chen, O Yang, C Sampat, P Bhalode, R Ramachandran, M Ierapetritou | 5 | |
Application of PSE Methods on Monoclonal Antibody Productivity Improvement and Quality Control O Yang, M Ierapetritou Computer Aided Chemical Engineering 49, 2215-2220, 2022 | 2 | 2022 |
PSE Tools and Challenges in the Development of Advanced Pharmaceutical Manufacturing Y Chen, P Bhalode, Y Ou, M Ierapetritou Computer Aided Chemical Engineering 49, 21-24, 2022 | 1 | 2022 |
Real-Time Statistical Process Monitoring A Nikolakopoulou, O Yang, G Bano The Digital Transformation of Product Formulation, 303-323, 2025 | | 2025 |
Application of a Computational Methodology for the Prediction of Mab Produced By CHO Cell Clones in pH Heterogeneous Bioreactors K Raudenbush, JV Reddy, L Attfield, O Kedge, P Kotidis, G Finka, ... 2024 AIChE Annual Meeting, 2024 | | 2024 |
14.2 REAL-TIME STATISTICAL PROCESS MONITORING A Nikolakopoulou, O Yang, G Bano The Digital Transformation of Product Formulation: Concepts, Challenges, and …, 2024 | | 2024 |
Optimization of Glucose Feeding Strategies of Fed-Batch Bioreactors for Monoclonal Antibody Production A Nikolakopoulou, O Yang, G Bano 2023 AIChE Annual Meeting, 2023 | | 2023 |
Development of a Computational Methodology for the Prediction of Mab Produced By CHO Cell Clones in Large Scale Bioreactors K Raudenbush, JV Reddy, L Attfield, P Kotidis, O Kedge, S Barodiya, ... 2023 AIChE Annual Meeting, 2023 | | 2023 |
Model-Based Insights on the Effect of Bioreactor pH and Temperature on N-Linked Glycosylation of Mabs Produced By CHO Cells JV Reddy, K Raudenbush, O Yang, A Gyorgypal, A Chaturvedi, ... 2022 AIChE Annual Meeting, 2022 | | 2022 |
Model-Based Investigation of Upstream CHO Cell Culture Process for Production of Monoclonal Antibodies with Desired N-Linked Glycosylation O Yang, JV Reddy, K Raudenbush, A Gyorgypal, S Chundawat, ... 2021 AIChE Annual Meeting, 2021 | | 2021 |