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Heath Skinner
Heath Skinner
University of Pittsburgh, UPMC Hillman Cancer Center
Dirección de correo verificada de upmc.edu - Página principal
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TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence
HD Skinner, VC Sandulache, TJ Ow, RE Meyn, JS Yordy, BM Beadle, ...
Clinical cancer research 18 (1), 290-300, 2012
3202012
Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1α, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT …
HD Skinner, JZ Zheng, J Fang, F Agani, BH Jiang
Journal of Biological Chemistry 279 (44), 45643-45651, 2004
3002004
Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation
G Zhou, J Wang, M Zhao, TX Xie, N Tanaka, D Sano, AA Patel, AM Ward, ...
Molecular cell 54 (6), 960-974, 2014
2452014
Association of body composition with survival and locoregional control of radiotherapy-treated head and neck squamous cell carcinoma
AJ Grossberg, S Chamchod, CD Fuller, ASR Mohamed, J Heukelom, ...
JAMA oncology 2 (6), 782-789, 2016
2212016
Prostate cancer cell proliferation is influenced by leptin1
P Somasundar, KA Frankenberry, H Skinner, G Vedula, DW McFadden, ...
Journal of Surgical Research 118 (1), 71-82, 2004
2062004
Salvage pembrolizumab added to kinase inhibitor therapy for the treatment of anaplastic thyroid carcinoma
PC Iyer, R Dadu, M Gule-Monroe, NL Busaidy, R Ferrarotto, MA Habra, ...
Journal for immunotherapy of cancer 6, 1-10, 2018
1882018
Evolutionary action score of TP53 identifies high-risk mutations associated with decreased survival and increased distant metastases in head and neck cancer
DM Neskey, AA Osman, TJ Ow, P Katsonis, T McDonald, SC Hicks, ...
Cancer research 75 (7), 1527-1536, 2015
1682015
Risk of late toxicity in men receiving dose-escalated hypofractionated intensity modulated prostate radiation therapy: results from a randomized trial
KE Hoffman, KR Voong, TJ Pugh, H Skinner, LB Levy, V Takiar, S Choi, ...
International Journal of Radiation Oncology* Biology* Physics 88 (5), 1074-1084, 2014
1662014
A novel YAP1 inhibitor targets CSC-enriched radiation-resistant cells and exerts strong antitumor activity in esophageal adenocarcinoma
S Song, M Xie, AW Scott, J Jin, L Ma, X Dong, HD Skinner, RL Johnson, ...
Molecular cancer therapeutics 17 (2), 443-454, 2018
1612018
Pathological complete response in patients with esophageal cancer after the trimodality approach: The association with baseline variables and survival—The University of Texas …
M Blum Murphy, L Xiao, VR Patel, DM Maru, AM Correa, F G. Amlashi, ...
Cancer 123 (21), 4106-4113, 2017
1512017
Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer
S Honjo, JA Ajani, AW Scott, Q Chen, HD Skinner, J Stroehlein, ...
International journal of oncology 45 (2), 567-574, 2014
1372014
Neoadjuvant BRAF-and immune-directed therapy for anaplastic thyroid carcinoma
ME Cabanillas, R Ferrarotto, AS Garden, S Ahmed, NL Busaidy, R Dadu, ...
Thyroid 28 (7), 945-951, 2018
1342018
Leptin receptor expression and cell signaling in breast cancer
KA Frankenberry, H Skinner, P Somasundar, DW McFadden, ...
International journal of oncology 28 (4), 985-993, 2006
1262006
Metformin use and improved response to therapy in esophageal adenocarcinoma
HD Skinner, MR McCurdy, AE Echeverria, SH Lin, JW Welsh, MS O'Reilly, ...
Acta Oncologica 52 (5), 1002-1009, 2013
1242013
ALDH-1 expression levels predict response or resistance to preoperative chemoradiation in resectable esophageal cancer patients
JA Ajani, X Wang, S Song, A Suzuki, T Taketa, K Sudo, R Wadhwa, ...
Molecular oncology 8 (1), 142-149, 2014
1222014
Clinical outcomes and patterns of disease recurrence after intensity modulated proton therapy for oropharyngeal squamous carcinoma
GB Gunn, P Blanchard, AS Garden, XR Zhu, CD Fuller, AS Mohamed, ...
International Journal of Radiation Oncology* Biology* Physics 95 (1), 360-367, 2016
1202016
Integrative analysis identifies a novel AXL–PI3 Kinase–PD-L1 signaling axis associated with radiation resistance in head and neck cancer
HD Skinner, U Giri, LP Yang, M Kumar, Y Liu, MD Story, CR Pickering, ...
Clinical Cancer Research 23 (11), 2713-2722, 2017
1172017
Metformin use and improved response to therapy in rectal cancer
HD Skinner, CH Crane, CR Garrett, C Eng, GJ Chang, JM Skibber, ...
Cancer medicine 2 (1), 99-107, 2013
1062013
Importance of surveillance and success of salvage strategies after definitive chemoradiation in patients with esophageal cancer
K Sudo, L Xiao, R Wadhwa, H Shiozaki, E Elimova, T Taketa, MA Blum, ...
Journal of Clinical Oncology 32 (30), 3400, 2014
1022014
Evolutionary action score of TP53 coding variants is predictive of platinum response in head and neck cancer patients
AA Osman, DM Neskey, P Katsonis, AA Patel, AM Ward, TK Hsu, ...
Cancer research 75 (7), 1205-1215, 2015
962015
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