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Heath Skinner
Heath Skinner
University of Pittsburgh, UPMC Hillman Cancer Center
Dirección de correo verificada de upmc.edu - Página principal
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TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence
HD Skinner, VC Sandulache, TJ Ow, RE Meyn, JS Yordy, BM Beadle, ...
Clinical cancer research 18 (1), 290-300, 2012
3192012
Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1α, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT …
HD Skinner, JZ Zheng, J Fang, F Agani, BH Jiang
Journal of Biological Chemistry 279 (44), 45643-45651, 2004
3052004
Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation
G Zhou, J Wang, M Zhao, TX Xie, N Tanaka, D Sano, AA Patel, AM Ward, ...
Molecular cell 54 (6), 960-974, 2014
2452014
Association of body composition with survival and locoregional control of radiotherapy-treated head and neck squamous cell carcinoma
AJ Grossberg, S Chamchod, CD Fuller, ASR Mohamed, J Heukelom, ...
JAMA oncology 2 (6), 782-789, 2016
2262016
Prostate cancer cell proliferation is influenced by leptin1
P Somasundar, KA Frankenberry, H Skinner, G Vedula, DW McFadden, ...
Journal of Surgical Research 118 (1), 71-82, 2004
2072004
Salvage pembrolizumab added to kinase inhibitor therapy for the treatment of anaplastic thyroid carcinoma
PC Iyer, R Dadu, M Gule-Monroe, NL Busaidy, R Ferrarotto, MA Habra, ...
Journal for immunotherapy of cancer 6, 1-10, 2018
1992018
Evolutionary action score of TP53 identifies high-risk mutations associated with decreased survival and increased distant metastases in head and neck cancer
DM Neskey, AA Osman, TJ Ow, P Katsonis, T McDonald, SC Hicks, ...
Cancer research 75 (7), 1527-1536, 2015
1672015
Risk of late toxicity in men receiving dose-escalated hypofractionated intensity modulated prostate radiation therapy: results from a randomized trial
KE Hoffman, KR Voong, TJ Pugh, H Skinner, LB Levy, V Takiar, S Choi, ...
International Journal of Radiation Oncology* Biology* Physics 88 (5), 1074-1084, 2014
1652014
A novel YAP1 inhibitor targets CSC-enriched radiation-resistant cells and exerts strong antitumor activity in esophageal adenocarcinoma
S Song, M Xie, AW Scott, J Jin, L Ma, X Dong, HD Skinner, RL Johnson, ...
Molecular cancer therapeutics 17 (2), 443-454, 2018
1632018
Pathological complete response in patients with esophageal cancer after the trimodality approach: The association with baseline variables and survival—The University of Texas …
M Blum Murphy, L Xiao, VR Patel, DM Maru, AM Correa, F G. Amlashi, ...
Cancer 123 (21), 4106-4113, 2017
1552017
Neoadjuvant BRAF-and immune-directed therapy for anaplastic thyroid carcinoma
ME Cabanillas, R Ferrarotto, AS Garden, S Ahmed, NL Busaidy, R Dadu, ...
Thyroid 28 (7), 945-951, 2018
1402018
Metformin sensitizes chemotherapy by targeting cancer stem cells and the mTOR pathway in esophageal cancer
S Honjo, JA Ajani, AW Scott, Q Chen, HD Skinner, J Stroehlein, ...
International journal of oncology 45 (2), 567-574, 2014
1372014
Leptin receptor expression and cell signaling in breast cancer
KA Frankenberry, H Skinner, P Somasundar, DW McFadden, ...
International journal of oncology 28 (4), 985-993, 2006
1282006
ALDH-1 expression levels predict response or resistance to preoperative chemoradiation in resectable esophageal cancer patients
JA Ajani, X Wang, S Song, A Suzuki, T Taketa, K Sudo, R Wadhwa, ...
Molecular oncology 8 (1), 142-149, 2014
1252014
Metformin use and improved response to therapy in esophageal adenocarcinoma
HD Skinner, MR McCurdy, AE Echeverria, SH Lin, JW Welsh, MS O'Reilly, ...
Acta Oncologica 52 (5), 1002-1009, 2013
1232013
Clinical outcomes and patterns of disease recurrence after intensity modulated proton therapy for oropharyngeal squamous carcinoma
GB Gunn, P Blanchard, AS Garden, XR Zhu, CD Fuller, AS Mohamed, ...
International Journal of Radiation Oncology* Biology* Physics 95 (1), 360-367, 2016
1222016
Integrative analysis identifies a novel AXL–PI3 Kinase–PD-L1 signaling axis associated with radiation resistance in head and neck cancer
HD Skinner, U Giri, LP Yang, M Kumar, Y Liu, MD Story, CR Pickering, ...
Clinical Cancer Research 23 (11), 2713-2722, 2017
1172017
Metformin use and improved response to therapy in rectal cancer
HD Skinner, CH Crane, CR Garrett, C Eng, GJ Chang, JM Skibber, ...
Cancer medicine 2 (1), 99-107, 2013
1062013
Importance of surveillance and success of salvage strategies after definitive chemoradiation in patients with esophageal cancer
K Sudo, L Xiao, R Wadhwa, H Shiozaki, E Elimova, T Taketa, MA Blum, ...
Journal of Clinical Oncology 32 (30), 3400-3405, 2014
1052014
Evolutionary action score of TP53 coding variants is predictive of platinum response in head and neck cancer patients
AA Osman, DM Neskey, P Katsonis, AA Patel, AM Ward, TK Hsu, ...
Cancer research 75 (7), 1205-1215, 2015
962015
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