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Kevin Coombes
Kevin Coombes
Professor of Population Health Sciences, Georgia Cancer Center at Augusta University
Dirección de correo verificada de augusta.edu - Página principal
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Comprehensive molecular portraits of human breast tumours
Brigham & Women’s Hospital & Harvard Medical School Chin Lynda 9 11 Park ...
Nature 490 (7418), 61-70, 2012
110272012
An epithelial–mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor …
LA Byers, L Diao, J Wang, P Saintigny, L Girard, M Peyton, L Shen, Y Fan, ...
Clinical cancer research 19 (1), 279-290, 2013
10032013
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
R Garzon, S Volinia, CG Liu, C Fernandez-Cymering, T Palumbo, ...
Blood, The Journal of the American Society of Hematology 111 (6), 3183-3189, 2008
8182008
Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments
KA Baggerly, JS Morris, KR Coombes
Bioinformatics 20 (5), 777-785, 2004
8002004
Co-occurring Genomic Alterations Define Major Subsets of KRAS-Mutant Lung Adenocarcinoma with Distinct Biology, Immune Profiles, and Therapeutic …
F Skoulidis, LA Byers, L Diao, VA Papadimitrakopoulou, P Tong, J Izzo, ...
Cancer discovery 5 (8), 860-877, 2015
7802015
Effect of KRAS Oncogene Substitutions on Protein Behavior: Implications for Signaling and Clinical Outcome
NT Ihle, LA Byers, ES Kim, P Saintigny, JJ Lee, GR Blumenschein, A Tsao, ...
Journal of the National Cancer Institute 104 (3), 228-239, 2012
5572012
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1
LA Byers, J Wang, MB Nilsson, J Fujimoto, P Saintigny, J Yordy, U Giri, ...
Cancer discovery 2 (9), 798-811, 2012
5142012
Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells
M Sun, Z Estrov, Y Ji, KR Coombes, DH Harris, R Kurzrock
Molecular cancer therapeutics 7 (3), 464-473, 2008
4992008
Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases
S Liu, M Umezu-Goto, M Murph, Y Lu, W Liu, F Zhang, S Yu, LC Stephens, ...
Cancer cell 15 (6), 539-550, 2009
4322009
A patient-derived, pan-cancer EMT signature identifies global molecular alterations and immune target enrichment following epithelial-to-mesenchymal transition
MP Mak, P Tong, L Diao, RJ Cardnell, DL Gibbons, WN William, ...
Clinical Cancer Research 22 (3), 609-620, 2016
4272016
Feature extraction and quantification for mass spectrometry in biomedical applications using the mean spectrum
JS Morris, KR Coombes, J Koomen, KA Baggerly, R Kobayashi
Bioinformatics 21 (9), 1764-1775, 2005
4152005
Improved peak detection and quantification of mass spectrometry data acquired from surface‐enhanced laser desorption and ionization by denoising spectra with the undecimated …
KR Coombes, S Tsavachidis, JS Morris, KA Baggerly, MC Hung, ...
Proteomics 5 (16), 4107-4117, 2005
4122005
Signal in noise: evaluating reported reproducibility of serum proteomic tests for ovarian cancer
KA Baggerly, JS Morris, SR Edmonson, KR Coombes
Journal of the National Cancer Institute 97 (4), 307-309, 2005
3782005
Deriving chemosensitivity from cell lines: forensic bioinformatics and reproducible research in high-throughput biology
KA Baggerly, KR Coombes
The Annals of Applied Statistics, 1309-1334, 2009
3432009
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival
S Rossi, M Shimizu, E Barbarotto, MS Nicoloso, F Dimitri, D Sampath, ...
Blood, The Journal of the American Society of Hematology 116 (6), 945-952, 2010
3032010
Quality control and peak finding for proteomics data collected from nipple aspirate fluid by surface-enhanced laser desorption and ionization
KR Coombes, HA Fritsche Jr, C Clarke, JN Chen, KA Baggerly, JS Morris, ...
Clinical chemistry 49 (10), 1615-1623, 2003
2852003
Functional proteomic profiling of AML predicts response and survival
SM Kornblau, R Tibes, YH Qiu, W Chen, HM Kantarjian, M Andreeff, ...
Blood, The Journal of the American Society of Hematology 113 (1), 154-164, 2009
2722009
A technical assessment of the utility of reverse phase protein arrays for the study of the functional proteome in non-microdissected human breast cancers
BT Hennessy, Y Lu, AM Gonzalez-Angulo, MS Carey, S Myhre, Z Ju, ...
Clinical proteomics 6, 129-151, 2010
2572010
Direct tandem mass spectrometry reveals limitations in protein profiling experiments for plasma biomarker discovery
JM Koomen, D Li, L Xiao, TC Liu, KR Coombes, J Abbruzzese, ...
Journal of proteome research 4 (3), 972-981, 2005
2482005
Prognostic impact and targeting of CRM1 in acute myeloid leukemia
K Kojima, SM Kornblau, V Ruvolo, A Dilip, S Duvvuri, RE Davis, M Zhang, ...
Blood, The Journal of the American Society of Hematology 121 (20), 4166-4174, 2013
2362013
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Artículos 1–20