Nozomi Nishimura
Nozomi Nishimura
Biomedical Engineering, Cornell University
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Deep tissue multiphoton microscopy using longer wavelength excitation
D Kobat, ME Durst, N Nishimura, AW Wong, CB Schaffer, C Xu
Optics express 17 (16), 13354-13364, 2009
Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain
AY Shih, JD Driscoll, PJ Drew, N Nishimura, CB Schaffer, D Kleinfeld
Journal of Cerebral Blood Flow & Metabolism 32 (7), 1277-1309, 2012
In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain
DG Ouzounov, T Wang, M Wang, DD Feng, NG Horton, ...
Nature methods 14 (4), 388-390, 2017
Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion
CB Schaffer, B Friedman, N Nishimura, LF Schroeder, PS Tsai, FF Ebner, ...
PLoS biology 4 (2), e22, 2006
Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative blood oxygenation level-dependent signal
A Devor, P Tian, N Nishimura, IC Teng, EMC Hillman, SN Narayanan, ...
Journal of Neuroscience 27 (16), 4452-4459, 2007
Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration
J Huynh, N Nishimura, K Rana, JM Peloquin, JP Califano, CR Montague, ...
Science translational medicine 3 (112), 112ra122-112ra122, 2011
Penetrating arterioles are a bottleneck in the perfusion of neocortex
N Nishimura, CB Schaffer, B Friedman, PD Lyden, D Kleinfeld
Proceedings of the National Academy of Sciences 104 (1), 365-370, 2007
Dynamics of femtosecond laser-induced breakdown in water from femtoseconds to microseconds
CB Schaffer, N Nishimura, EN Glezer, AMT Kim, E Mazur
Optics express 10 (3), 196-203, 2002
Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models
JC Cruz Hernández, O Bracko, CJ Kersbergen, V Muse, ...
Nature neuroscience 22 (3), 413-420, 2019
Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke
N Nishimura, CB Schaffer, B Friedman, PS Tsai, PD Lyden, D Kleinfeld
Nature methods 3 (2), 99-108, 2006
Preventing dementia by preventing stroke: the Berlin Manifesto
V Hachinski, K Einhäupl, D Ganten, S Alladi, C Brayne, BCM Stephan, ...
Alzheimer's & Dementia 15 (7), 961-984, 2019
In vivo two-photon excited fluorescence microscopy reveals cardiac-and respiration-dependent pulsatile blood flow in cortical blood vessels in mice
TP Santisakultarm, NR Cornelius, N Nishimura, AI Schafer, RT Silver, ...
American Journal of Physiology-Heart and Circulatory Physiology 302 (7 …, 2012
Limitations of collateral flow after occlusion of a single cortical penetrating arteriole
N Nishimura, NL Rosidi, C Iadecola, CB Schaffer
Journal of Cerebral Blood Flow & Metabolism 30 (12), 1914-1927, 2010
Preictal and ictal neurovascular and metabolic coupling surrounding a seizure focus
M Zhao, J Nguyen, H Ma, N Nishimura, CB Schaffer, TH Schwartz
Journal of Neuroscience 31 (37), 13292-13300, 2011
Principles, design, and construction of a two photon laser scanning microscope for in vitro and in vivo brain imaging
PS Tsai, N Nishimura, EJ Yoder, EM Dolnick, GA White, D Kleinfeld
In vivo optical imaging of brain function, 113-171, 2002
Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries
J Nguyen, N Nishimura, RN Fetcho, C Iadecola, CB Schaffer
Journal of Cerebral Blood Flow & Metabolism 31 (11), 2243-2254, 2011
Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations
X Zhou, L Sun, O Bracko, JW Choi, Y Jia, AL Nana, OA Brady, ...
Nature communications 8 (1), 15277, 2017
Minimally disruptive laser-induced breakdown in water
EN Glezer, CB Schaffer, N Nishimura, E Mazur
Optics letters 22 (23), 1817-1819, 1997
Robust and fragile aspects of cortical blood flow in relation to the underlying angioarchitecture
AY Shih, C Rühlmann, P Blinder, A Devor, PJ Drew, B Friedman, ...
Microcirculation 22 (3), 204-218, 2015
Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degeneration
NL Rosidi, J Zhou, S Pattanaik, P Wang, W Jin, M Brophy, WL Olbricht, ...
PloS one 6 (10), e26612, 2011
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