Andy Y. Shih
Andy Y. Shih
Seattle Children's Research Institute & University of Washington
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Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress
AY Shih, DA Johnson, G Wong, AD Kraft, L Jiang, H Erb, JA Johnson, ...
Journal of Neuroscience 23 (8), 3394-3406, 2003
A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo
AY Shih, P Li, TH Murphy
Journal of Neuroscience 25 (44), 10321-10335, 2005
Two-photon microscopy as a tool to study blood flow and neurovascular coupling in the rodent brain
AY Shih, JD Driscoll, PJ Drew, N Nishimura, CB Schaffer, D Kleinfeld
Journal of Cerebral Blood Flow & Metabolism 32 (7), 1277-1309, 2012
Chronic optical access through a polished and reinforced thinned skull
PJ Drew, AY Shih, JD Driscoll, PM Knutsen, P Blinder, D Davalos, ...
Nature methods 7 (12), 981-984, 2010
NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons
JM Lee, AY Shih, TH Murphy, JA Johnson
Journal of Biological Chemistry 278 (39), 37948-37956, 2003
The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit
AY Shih, P Blinder, PS Tsai, B Friedman, G Stanley, PD Lyden, ...
Nature neuroscience 16 (1), 55-63, 2013
Cystine/glutamate exchange modulates glutathione supply for neuroprotection from oxidative stress and cell proliferation
AY Shih, H Erb, X Sun, S Toda, PW Kalivas, TH Murphy
Journal of Neuroscience 26 (41), 10514-10523, 2006
Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo
AY Shih, S Imbeault, V Barakauskas, H Erb, L Jiang, P Li, TH Murphy
Journal of Biological Chemistry 280 (24), 22925-22936, 2005
Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice
DA Hartmann, RG Underly, RI Grant, AN Watson, V Lindner, AY Shih
Neurophotonics 2 (4), 041402-041402, 2015
Fluctuating and sensory-induced vasodynamics in rodent cortex extend arteriole capacity
PJ Drew, AY Shih, D Kleinfeld
Proceedings of the National Academy of Sciences 108 (20), 8473-8478, 2011
Detection, risk factors, and functional consequences of cerebral microinfarcts
SJ van Veluw, AY Shih, EE Smith, C Chen, JA Schneider, JM Wardlaw, ...
The Lancet Neurology 16 (9), 730-740, 2017
Entrainment of arteriole vasomotor fluctuations by neural activity is a basis of blood-oxygenation-level-dependent “resting-state” connectivity
C Mateo, PM Knutsen, PS Tsai, AY Shih, D Kleinfeld
Neuron 96 (4), 936-948. e3, 2017
Brain capillary pericytes exert a substantial but slow influence on blood flow
DA Hartmann, AA Berthiaume, RI Grant, SA Harrill, T Koski, T Tieu, ...
Nature neuroscience 24 (5), 633-645, 2021
Organizational hierarchy and structural diversity of microvascular pericytes in adult mouse cortex
RI Grant, DA Hartmann, RG Underly, AA Berthiaume, NR Bhat, AY Shih
Journal of Cerebral Blood Flow & Metabolism 39 (3), 411-425, 2019
Topological basis for the robust distribution of blood to rodent neocortex
P Blinder, AY Shih, C Rafie, D Kleinfeld
Proceedings of the National Academy of Sciences 107 (28), 12670-12675, 2010
Pericytes as inducers of rapid, matrix metalloproteinase-9-dependent capillary damage during ischemia
RG Underly, M Levy, DA Hartmann, RI Grant, AN Watson, AY Shih
Journal of Neuroscience 37 (1), 129-140, 2017
Dynamic remodeling of pericytes in vivo maintains capillary coverage in the adult mouse brain
AA Berthiaume, RI Grant, KP McDowell, RG Underly, DA Hartmann, ...
Cell reports 22 (1), 8-16, 2018
Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke
AY Shih, B Friedman, PK Drew, PS Tsai, PD Lyden, D Kleinfeld
Journal of Cerebral Blood Flow & Metabolism 29 (4), 738-751, 2009
Rapid determination of particle velocity from space-time images using the Radon transform
PJ Drew, P Blinder, G Cauwenberghs, AY Shih, D Kleinfeld
Journal of computational neuroscience 29, 5-11, 2010
A polished and reinforced thinned-skull window for long-term imaging of the mouse brain
AY Shih, C Mateo, PJ Drew, PS Tsai, D Kleinfeld
JoVE (Journal of Visualized Experiments), e3742, 2012
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Artículos 1–20