Role of the CXCL8-CXCR1/2 axis in cancer and inflammatory diseases H Ha, B Debnath, N Neamati Theranostics 7 (6), 1543, 2017 | 726 | 2017 |
Small molecule inhibitors of CXCR4 B Debnath, S Xu, F Grande, A Garofalo, N Neamati Theranostics 3 (1), 47, 2013 | 318 | 2013 |
Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment S Xu, AN Butkevich, R Yamada, Y Zhou, B Debnath, R Duncan, E Zandi, ... Proceedings of the National Academy of Sciences 109 (40), 16348-16353, 2012 | 252 | 2012 |
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein B Debnath, S Xu, N Neamati Journal of medicinal chemistry 55 (15), 6645-6668, 2012 | 238 | 2012 |
Fragment-based discovery of 8-hydroxyquinoline inhibitors of the hiv-1 integrase–lens epithelium-derived growth factor/p75 (in–ledgf/p75) interaction E Serrao, B Debnath, H Otake, Y Kuang, F Christ, Z Debyser, N Neamati Journal of medicinal chemistry 56 (6), 2311-2322, 2013 | 83 | 2013 |
The hydroxyquinoline analogue YUM70 inhibits GRP78 to induce ER stress–mediated apoptosis in pancreatic cancer S Samanta, S Yang, B Debnath, D Xue, Y Kuang, K Ramkumar, AS Lee, ... Cancer research 81 (7), 1883-1895, 2021 | 82 | 2021 |
Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: A scaffold hopping approach using salicylate and catechol groups X Fan, FH Zhang, RI Al-Safi, LF Zeng, Y Shabaik, B Debnath, ... Bioorganic & medicinal chemistry 19 (16), 4935-4952, 2011 | 73 | 2011 |
Structure-based optimization of a novel class of aldehyde dehydrogenase 1A (ALDH1A) subfamily-selective inhibitors as potential adjuncts to ovarian cancer chemotherapy BC Huddle, E Grimley, CD Buchman, M Chtcherbinine, B Debnath, ... Journal of medicinal chemistry 61 (19), 8754-8773, 2018 | 70 | 2018 |
Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1, 6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties LF Zeng, Y Wang, R Kazemi, S Xu, ZL Xu, TW Sanchez, LM Yang, ... Journal of Medicinal Chemistry 55 (22), 9492-9509, 2012 | 70 | 2012 |
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells SM Stanford, D Krishnamurthy, MD Falk, R Messina, B Debnath, S Li, ... Journal of medicinal chemistry 54 (6), 1640-1654, 2011 | 69 | 2011 |
QSAR study on some pyridoacridine ascididemin analogues as anti-tumor agents B Debnath, S Gayen, S Bhattacharya, S Samanta, T Jha Bioorganic & medicinal chemistry 11 (24), 5493-5499, 2003 | 66 | 2003 |
Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor K Ramkumar, S Samanta, A Kyani, S Yang, S Tamura, E Ziemke, ... Nature communications 7 (1), 13084, 2016 | 61 | 2016 |
5-N-Substituted-2-(substituted benzenesulphonyl) glutamines as antitumor agents. Part II: Synthesis, biological activity and QSAR study S Samanta, K Srikanth, S Banerjee, B Debnath, S Gayen, T Jha Bioorganic & medicinal chemistry 12 (6), 1413-1423, 2004 | 58 | 2004 |
QSAR study on some anti-HIV HEPT analogues using physicochemical and topological parameters S Gayen, B Debnath, S Samanta, T Jha Bioorganic & medicinal chemistry 12 (6), 1493-1503, 2004 | 57 | 2004 |
Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase–LEDGF/p75 interaction E Serrao, ZL Xu, B Debnath, F Christ, Z Debyser, YQ Long, N Neamati Bioorganic & medicinal chemistry 21 (19), 5963-5972, 2013 | 55 | 2013 |
Synergistic effect of methanol extract of Abies webbiana leaves on sleeping time induced by standard sedatives in mice and anti-inflammatory activity of extracts in rats SS Nayak, AK Ghosh, B Debnath, SP Vishnoi, T Jha Journal of ethnopharmacology 93 (2-3), 397-402, 2004 | 51 | 2004 |
Syntheses, biological evaluation and QSAR study on antitumor activity of 1, 5-N, N′-disubstituted-2-(substituted benzenesulphonyl) glutamamides K Srikanth, B Debnath, T Jha Bioorganic & medicinal chemistry 10 (6), 1841-1854, 2002 | 51 | 2002 |
QSAR study on some p-arylthio cinnamides as antagonists of biochemical ICAM-1/LFA-1 interaction and ICAM-1/JY-8 cell adhesion in relation to anti-inflammatory activity B Debnath, S Samanta, K Roy, T Jha Bioorganic & medicinal chemistry 11 (8), 1615-1619, 2003 | 46 | 2003 |
1,5-N,N'-Disubstituted-2-(Substituted Benzenesulphonyl)glutamamides as Antitumor Agents. Part 2. Synthesis, Biological Activity and QSAR Study B Debnath, K Srikanth, S Banarjee, T Jha Internet Electronic Journal of Molecular Design 1 (10), 488-502, 2002 | 44* | 2002 |
Exploring QSAR on 3-aminopyrazoles as antitumor agents for their inhibitory activity of CDK2/cyclin A S Samanta, B Debnath, A Basu, S Gayen, K Srikanth, T Jha European journal of medicinal chemistry 41 (10), 1190-1195, 2006 | 43 | 2006 |