Postmitotic neurons develop a p21‐dependent senescence‐like phenotype driven by a DNA damage response D Jurk, C Wang, S Miwa, M Maddick, V Korolchuk, A Tsolou, ES Gonos, ... Aging cell 11 (6), 996-1004, 2012 | 593 | 2012 |
Clusterin/apolipoprotein J in human aging and cancer IP Trougakos, ES Gonos The international journal of biochemistry & cell biology 34 (11), 1430-1448, 2002 | 507 | 2002 |
Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast P Dumont, M Burton, QM Chen, ES Gonos, C Frippiat, JB Mazarati, ... Free Radical Biology and Medicine 28 (3), 361-373, 2000 | 468 | 2000 |
Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases AL Cardoso, A Fernandes, JA Aguilar-Pimentel, MH de Angelis, ... Ageing research reviews 47, 214-277, 2018 | 431 | 2018 |
Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its … N Chondrogianni, FLL Stratford, IP Trougakos, B Friguet, AJ Rivett, ... Journal of Biological Chemistry 278 (30), 28026-28037, 2003 | 398 | 2003 |
Protein damage, repair and proteolysis N Chondrogianni, I Petropoulos, S Grimm, K Georgila, B Catalgol, ... Molecular aspects of medicine 35, 1-71, 2014 | 307 | 2014 |
Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell … IP Trougakos, A So, B Jansen, ME Gleave, ES Gonos Cancer research 64 (5), 1834-1842, 2004 | 298 | 2004 |
MARK-AGE biomarkers of ageing A Bürkle, M Moreno-Villanueva, J Bernhard, M Blasco, G Zondag, ... Mechanisms of ageing and development 151, 2-12, 2015 | 293 | 2015 |
Anti-ageing and rejuvenating effects of quercetin N Chondrogianni, S Kapeta, I Chinou, K Vassilatou, I Papassideri, ... Experimental gerontology 45 (10), 763-771, 2010 | 254 | 2010 |
Overexpression of Proteasome β5 Assembled Subunit Increases the Amount of Proteasome and Confers Ameliorated Response to Oxidative Stress and Higher Survival Rates*[boxs] N Chondrogianni, C Tzavelas, AJ Pemberton, IP Nezis, AJ Rivett, ... Journal of Biological Chemistry 280 (12), 11840-11850, 2005 | 254 | 2005 |
Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts S Kapeta, N Chondrogianni, ES Gonos Journal of Biological Chemistry 285 (11), 8171-8184, 2010 | 245 | 2010 |
Fibroblast cultures from healthy centenarians have an active proteasome N Chondrogianni, I Petropoulos, C Franceschi, B Friguet, ES Gonos Experimental gerontology 35 (6-7), 721-728, 2000 | 230 | 2000 |
The Olive Constituent Oleuropein Exhibits Proteasome Stimulatory Properties In Vitro and Confers Life Span Extension of Human Embryonic Fibroblasts M Katsiki, N Chondrogianni, I Chinou, AJ Rivett, ES Gonos Rejuvenation Research 10 (2), 157-172, 2007 | 229 | 2007 |
Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases IP Trougakos, ES Gonos Free radical research 40 (12), 1324-1334, 2006 | 220 | 2006 |
Chemical analysis of Greek pollen-Antioxidant, antimicrobial and proteasome activation properties K Graikou, S Kapeta, N Aligiannis, G Sotiroudis, N Chondrogianni, ... Chemistry Central Journal 5, 1-9, 2011 | 219 | 2011 |
Genome‐wide linkage analysis for human longevity: Genetics of Healthy Aging Study M Beekman, H Blanché, M Perola, A Hervonen, V Bezrukov, E Sikora, ... Aging cell 12 (2), 184-193, 2013 | 211 | 2013 |
Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex IP Trougakos, M Lourda, MH Antonelou, D Kletsas, VG Gorgoulis, ... Clinical cancer research 15 (1), 48-59, 2009 | 201 | 2009 |
The genetics of human longevity M Capri, S Salvioli, F Sevini, S Valensin, L Celani, D Monti, G Pawelec, ... Annals of the New York Academy of Sciences 1067 (1), 252-263, 2006 | 193 | 2006 |
20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegans N Chondrogianni, K Georgila, N Kourtis, N Tavernarakis, ES Gonos The FASEB Journal 29 (2), 611, 2014 | 189 | 2014 |
Proteasome dysfunction in mammalian aging: steps and factors involved N Chondrogianni, ES Gonos Experimental gerontology 40 (12), 931-938, 2005 | 175 | 2005 |