L. David Sibley
L. David Sibley
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Toxoplasma gondii Comprises Three Clonal Lineages: Correlation of Parasite Genotype with Human Disease
DK Howe, LD Sibley
Journal of infectious diseases 172 (6), 1561-1566, 1995
Virulent strains of Toxoplasma gondii comprise a single clonal lineage
LD Sibley, JC Boothroyd
Nature 359 (6390), 82-85, 1992
Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts.
VB Carruthers, LD Sibley
European journal of cell biology 73 (2), 114-123, 1997
Toxoplasma invasion of mammalian cells is powered by the actin cytoskeleton of the parasite
JM Dobrowolski, LD Sibley
Cell 84 (6), 933-939, 1996
Cytoskeleton of apicomplexan parasites
NS Morrissette, LD Sibley
Microbiology and molecular biology reviews 66 (1), 21-38, 2002
Polymorphic secreted kinases are key virulence factors in toxoplasmosis
JPJ Saeij, JP Boyle, S Coller, S Taylor, LD Sibley, ET Brooke-Powell, ...
Science 314 (5806), 1780-1783, 2006
Determination of genotypes of Toxoplasma gondii strains isolated from patients with toxoplasmosis
DK Howe, S Honoré, F Derouin, LD Sibley
Journal of clinical microbiology 35 (6), 1411-1414, 1997
Modulation of innate immunity by Toxoplasma gondii virulence effectors
CA Hunter, LD Sibley
Nature Reviews Microbiology 10 (11), 766-778, 2012
A Secreted Serine-Threonine Kinase Determines Virulence in the Eukaryotic Pathogen Toxoplasma gondii
S Taylor, A Barragan, C Su, B Fux, SJ Fentress, K Tang, WL Beatty, ...
Science 314 (5806), 1776-1780, 2006
Intracellular parasite invasion strategies
LD Sibley
Science 304 (5668), 248-253, 2004
Gr1+ inflammatory monocytes are required for mucosal resistance to the pathogen Toxoplasma gondii
IR Dunay, RA DaMatta, B Fux, R Presti, S Greco, M Colonna, LD Sibley
Immunity 29 (2), 306-317, 2008
Acute toxoplasmosis leads to lethal overproduction of Th1 cytokines
DG Mordue, F Monroy, M La Regina, CA Dinarello, LD Sibley
The Journal of Immunology 167 (8), 4574-4584, 2001
Autophagosome-independent essential function for the autophagy protein Atg5 in cellular immunity to intracellular pathogens
Z Zhao, B Fux, M Goodwin, IR Dunay, D Strong, BC Miller, K Cadwell, ...
Cell host & microbe 4 (5), 458-469, 2008
Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9
B Shen, KM Brown, TD Lee, LD Sibley
MBio 5 (3), 10.1128/mbio. 01114-14, 2014
Compensatory dendritic cell development mediated by BATF–IRF interactions
R Tussiwand, WL Lee, TL Murphy, M Mashayekhi, W Kc, JC Albring, ...
Nature 490 (7421), 502-507, 2012
CD8α+ dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites
M Mashayekhi, MM Sandau, IR Dunay, EM Frickel, A Khan, ...
Immunity 35 (2), 249-259, 2011
Mobilization of intracellular calcium stimulates microneme discharge in Toxoplasma gondii
VB Carruthers, LD Sibley
Molecular microbiology 31 (2), 421-428, 1999
Secretion of micronemal proteins is associated with Toxoplasma invasion of host cells
VB Carruthers, OK Giddings, LD Sibley
Cellular microbiology 1 (3), 225-235, 1999
Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages
C Su, A Khan, P Zhou, D Majumdar, D Ajzenberg, ML Dardé, XQ Zhu, ...
Proceedings of the National Academy of Sciences 109 (15), 5844-5849, 2012
Recent expansion of Toxoplasma through enhanced oral transmission
C Su, D Evans, RH Cole, JC Kissinger, JW Ajioka, LD Sibley
Science 299 (5605), 414-416, 2003
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