Brian Crouch, PhD
Brian Crouch, PhD
Assistant Research Professor, Department of Biomedical Engineering, Duke University
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Near-simultaneous intravital microscopy of glucose uptake and mitochondrial membrane potential, key endpoints that reflect major metabolic axes in cancer
C Zhu, AF Martinez, HL Martin, M Li, BT Crouch, DA Carlson, ...
Scientific reports 7 (1), 13772, 2017
Metaboloptics: Visualization of the tumor functional landscape via metabolic and vascular imaging
AF Martinez, SS McCachren III, M Lee, HA Murphy, C Zhu, BT Crouch, ...
Scientific Reports 8 (1), 4171, 2018
Optical imaging of glucose uptake and mitochondrial membrane potential to characterize Her2 breast tumor metabolic phenotypes
MC Madonna, DB Fox, BT Crouch, J Lee, C Zhu, AF Martinez, JV Alvarez, ...
Molecular Cancer Research 17 (7), 1545-1555, 2019
In vivo optical metabolic imaging of long-chain fatty acid uptake in orthotopic models of triple-negative breast cancer
MC Madonna, JE Duer, JV Lee, J Williams, B Avsaroglu, C Zhu, ...
Cancers 13 (1), 148, 2021
Leveraging ectopic Hsp90 expression to assay the presence of tumor cells and aggressive tumor phenotypes in breast specimens
B Crouch, H Murphy, S Belonwu, A Martinez, J Gallagher, A Hall, MS Soo, ...
Scientific reports 7 (1), 17487, 2017
Polymer-assisted intratumoral delivery of ethanol: Preclinical investigation of safety and efficacy in a murine breast cancer model
C Nief, R Morhard, E Chelales, D Adrianzen Alvarez, I Bourla BS, CT Lam, ...
PLoS One 16 (1), e0234535, 2021
Spiritual well-being and its association with health-related quality of life in primary brain tumor patients
DM Randazzo, F McSherry, JE Herndon, ML Affronti, ES Lipp, ES Miller, ...
Neuro-Oncology Practice 8 (3), 299-309, 2021
Exploiting heat shock protein expression to develop a non-invasive diagnostic tool for breast cancer
BT Crouch, J Gallagher, R Wang, J Duer, A Hall, MS Soo, P Hughes, ...
Scientific Reports 9 (1), 3461, 2019
Radiologic-pathologic analysis of increased ethanol localization and ablative extent achieved by ethyl cellulose
E Chelales, R Morhard, C Nief, B Crouch, JI Everitt, AA Sag, ...
Scientific Reports 11 (1), 20700, 2021
Near-simultaneous quantification of glucose uptake, mitochondrial membrane potential, and vascular parameters in murine flank tumors using quantitative diffuse reflectance and …
C Zhu, HL Martin, BT Crouch, AF Martinez, M Li, GM Palmer, ...
Biomedical Optics Express 9 (7), 3399-3412, 2018
Simultaneous in vivo optical quantification of key metabolic and vascular endpoints reveals tumor metabolic diversity in murine breast tumor models
C Zhu, M Li, T Vincent, HL Martin, BT Crouch, AF Martinez, MC Madonna, ...
Journal of biophotonics 12 (4), e201800372, 2019
Optimizing ethyl cellulose-ethanol delivery towards enabling ablation of cervical dysplasia
JL Mueller, R Morhard, M DeSoto, E Chelales, J Yang, C Nief, B Crouch, ...
Scientific Reports 11 (1), 16869, 2021
Multicontrast pocket colposcopy cervical cancer diagnostic algorithm for referral populations
N AsieduMercy
BME frontiers, 2022
Targeting tumor acidosis and regulatory T cells unmasks anti-metastatic potential of local tumor ablation in triple-negative breast cancer
CA Nief, A Gonzales, E Chelales, JS Agudogo, BT Crouch, SK Nair, ...
International journal of molecular sciences 23 (15), 8479, 2022
Adaptive design of fluorescence imaging systems for custom resolution, fields of view, and geometries
R Wang, RJ Deutsch, ED Sunassee, BT Crouch, N Ramanujam
BME frontiers 4, 0005, 2023
In vivo metabolic imaging identifies lipid vulnerability in a preclinical model of Her2+/Neu breast cancer residual disease and recurrence
MC Madonna, JE Duer, BJ McKinney, ED Sunassee, BT Crouch, ...
NPJ Breast Cancer 8 (1), 111, 2022
A Spectroscopic Technique to Simultaneously Characterize Fatty Acid Uptake, Mitochondrial Activity, Vascularity, and Oxygen Saturation for Longitudinal Studies In Vivo
RJ Deutsch, VW D’Agostino, ED Sunassee, M Kwan, MC Madonna, ...
Metabolites 12 (5), 369, 2022
Understanding the sources of errors in ex vivo Hsp90 molecular imaging for rapid-on-site breast cancer diagnosis
R Wang, DA Alvarez, BT Crouch, A Pilani, C Lam, C Zhu, P Hughes, ...
Biomedical Optics Express 12 (4), 2299-2311, 2021
Optimizing fluorescently tethered Hsp90 inhibitor dose for maximal specific uptake by breast tumors
BT Crouch, J Duer, R Wang, J Gallagher, A Hall, MS Soo, P Hughes, ...
Molecular-Guided Surgery: Molecules, Devices, and Applications IV 10478, 1047804, 2018
Evaluating Tumor Hypoxia Radiosensitization Via Electron Paramagnetic Resonance Oxygen Imaging (EPROI)
AG Rickard, YM Mowery, A Bassil, DC Rouse, NT Williams, T Charity, ...
Molecular Imaging and Biology, 1-13, 2023
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