Kristin M. Riching
Kristin M. Riching
Promega Corporation
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Aligned collagen is a prognostic signature for survival in human breast carcinoma
MW Conklin, JC Eickhoff, KM Riching, CA Pehlke, KW Eliceiri, ...
The American journal of pathology 178 (3), 1221-1232, 2011
In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia
MC Skala, KM Riching, A Gendron-Fitzpatrick, J Eickhoff, KW Eliceiri, ...
Proceedings of the National Academy of Sciences 104 (49), 19494-19499, 2007
3D collagen alignment limits protrusions to enhance breast cancer cell persistence
KM Riching, BL Cox, MR Salick, C Pehlke, AS Riching, SM Ponik, ...
Biophysical journal 107 (11), 2546-2558, 2014
In vivo multiphoton fluorescence lifetime imaging<?xpp qa?> of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia
MC Skala, KM Riching, DK Bird, A Gendron-Fitzpatrick, J Eickhoff, ...
Journal of biomedical optics 12 (2), 024014-024014-10, 2007
Iterative design and optimization of initially inactive proteolysis targeting chimeras (PROTACs) identify VZ185 as a potent, fast, and selective von Hippel–Lindau (VHL) based …
V Zoppi, SJ Hughes, C Maniaci, A Testa, T Gmaschitz, C Wieshofer, ...
Journal of medicinal chemistry 62 (2), 699-726, 2018
Quantitative live-cell kinetic degradation and mechanistic profiling of PROTAC mode of action
KM Riching, S Mahan, CR Corona, M McDougall, JD Vasta, MB Robers, ...
ACS chemical biology 13 (9), 2758-2770, 2018
Filamin A–β1 integrin complex tunes epithelial cell response to matrix tension
S Gehler, M Baldassarre, Y Lad, JL Leight, MA Wozniak, KM Riching, ...
Molecular biology of the cell 20 (14), 3224-3238, 2009
Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity
S Imaide, KM Riching, N Makukhin, V Vetma, C Whitworth, SJ Hughes, ...
Nature chemical biology 17 (11), 1157-1167, 2021
A three-dimensional computational model of collagen network mechanics
B Lee, X Zhou, K Riching, KW Eliceiri, PJ Keely, SA Guelcher, AM Weaver, ...
PloS one 9 (11), e111896, 2014
Discovery and resistance mechanism of a selective CDK12 degrader
B Jiang, Y Gao, J Che, W Lu, IH Kaltheuner, R Dries, M Kalocsay, ...
Nature chemical biology 17 (6), 675-683, 2021
Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression
S Gehler, SM Ponik, KM Riching, PJ Keely
Critical Reviews™ in Eukaryotic Gene Expression 23 (2), 2013
Monitoring and deciphering protein degradation pathways inside cells
DL Daniels, KM Riching, M Urh
Drug Discovery Today: Technologies 31, 61-68, 2019
Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor …
LE Kilpatrick, R Friedman-Ohana, DC Alcobia, K Riching, CJ Peach, ...
Biochemical Pharmacology 136, 62-75, 2017
R-Ras regulates β1-integrin trafficking via effects on membrane ruffling and endocytosis
MW Conklin, A Ada-Nguema, M Parsons, KM Riching, PJ Keely
BMC cell biology 11, 1-15, 2010
In vivo multiphoton fluorescence lifetime imaging of protein-bound and free NADH in normal and pre-cancerous epithelia
MC Skala, KM Riching, DK Bird, A Gendron-Fitzpatrick, J Eickhoff, ...
Journal of biomedical optics 12 (2), 024014, 2007
Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs
N Bai, KM Riching, A Makaju, H Wu, TM Acker, SC Ou, Y Zhang, X Shen, ...
Journal of Biological Chemistry 298 (4), 2022
Effect of optical clearing agents on the in vivo optical properties of squamous epithelial tissue
SR Millon, KM Roldan‐Perez, KM Riching, GM Palmer, N Ramanujam
Lasers in Surgery and Medicine: The Official Journal of the American Society …, 2006
CDK family PROTAC profiling reveals distinct kinetic responses and cell cycle–dependent degradation of CDK2
KM Riching, MK Schwinn, JD Vasta, MB Robers, T Machleidt, M Urh, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (4), 560-569, 2021
Preparation of 3D collagen gels and microchannels for the study of 3D interactions in vivo
B Burkel, BA Morris, SM Ponik, KM Riching, KW Eliceiri, PJ Keely
JoVE (Journal of Visualized Experiments), e53989, 2016
Targeted protein degradation phenotypic studies using HaloTag CRISPR/Cas9 endogenous tagging coupled with HaloPROTAC3
EA Caine, SD Mahan, RL Johnson, AN Nieman, N Lam, CR Warren, ...
Current Protocols in Pharmacology 91 (1), e81, 2020
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