Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3563 | 2017 |
The GTEx Consortium atlas of genetic regulatory effects across human tissues GTEx Consortium Science 369 (6509), 1318-1330, 2020 | 3104 | 2020 |
Landscape of X chromosome inactivation across human tissues T Tukiainen, AC Villani, A Yen, MA Rivas, JL Marshall, R Satija, M Aguirre, ... Nature 550 (7675), 244-248, 2017 | 933 | 2017 |
The impact of sex on gene expression across human tissues M Oliva, M Muñoz-Aguirre, S Kim-Hellmuth, V Wucher, ADH Gewirtz, ... Science 369 (6509), eaba3066, 2020 | 813 | 2020 |
Underspecification presents challenges for credibility in modern machine learning A D'Amour, K Heller, D Moldovan, B Adlam, B Alipanahi, A Beutel, ... Journal of Machine Learning Research 23 (226), 1-61, 2022 | 795 | 2022 |
Colocalization of GWAS and eQTL signals detects target genes F Hormozdiari, M Van De Bunt, AV Segre, X Li, JWJ Joo, M Bilow, JH Sul, ... The American Journal of Human Genetics 99 (6), 1245-1260, 2016 | 738 | 2016 |
Genome sequencing highlights the dynamic early history of dogs AH Freedman, I Gronau, RM Schweizer, D Ortega-Del Vecchyo, E Han, ... PLoS genetics 10 (1), e1004016, 2014 | 718 | 2014 |
Chromosome conformation elucidates regulatory relationships in developing human brain H Won, L de La Torre-Ubieta, JL Stein, NN Parikshak, J Huang, ... Nature 538 (7626), 523-527, 2016 | 598 | 2016 |
Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 589 | 2017 |
Integrating functional data to prioritize causal variants in statistical fine-mapping studies G Kichaev, WY Yang, S Lindstrom, F Hormozdiari, E Eskin, AL Price, ... PLoS genetics 10 (10), e1004722, 2014 | 563 | 2014 |
Identifying causal variants at loci with multiple signals of association F Hormozdiari, E Kostem, EY Kang, B Pasaniuc, E Eskin Proceedings of the 5th ACM Conference on Bioinformatics, Computational …, 2014 | 502 | 2014 |
Using an atlas of gene regulation across 44 human tissues to inform complex disease-and trait-associated variation ER Gamazon, AV Segrè, M Van De Bunt, X Wen, HS Xi, F Hormozdiari, ... Nature genetics 50 (7), 956-967, 2018 | 447 | 2018 |
Loci associated with skin pigmentation identified in African populations NG Crawford, DE Kelly, MEB Hansen, MH Beltrame, S Fan, SL Bowman, ... Science 358 (6365), eaan8433, 2017 | 379 | 2017 |
A quantitative proteome map of the human body L Jiang, M Wang, S Lin, R Jian, X Li, J Chan, G Dong, H Fang, ... Cell 183 (1), 269-283. e19, 2020 | 349 | 2020 |
mrsFAST: a cache-oblivious algorithm for short-read mapping F Hach, F Hormozdiari, C Alkan, F Hormozdiari, I Birol, EE Eichler, ... Nature methods 7 (8), 576-577, 2010 | 344 | 2010 |
The impact of rare variation on gene expression across tissues X Li, Y Kim, EK Tsang, JR Davis, FN Damani, C Chiang, GT Hess, ... Nature 550 (7675), 239-243, 2017 | 273 | 2017 |
Applicability domains for classification problems: benchmarking of distance to models for Ames mutagenicity set I Sushko, S Novotarskyi, R Körner, AK Pandey, A Cherkasov, J Li, ... Journal of chemical information and modeling 50 (12), 2094-2111, 2010 | 273 | 2010 |
Functionally informed fine-mapping and polygenic localization of complex trait heritability O Weissbrod, F Hormozdiari, C Benner, R Cui, J Ulirsch, S Gazal, ... Nature genetics 52 (12), 1355-1363, 2020 | 264 | 2020 |
Exploiting the GTEx resources to decipher the mechanisms at GWAS loci AN Barbeira, R Bonazzola, ER Gamazon, Y Liang, YS Park, ... Genome biology 22, 1-24, 2021 | 247 | 2021 |
Extreme polygenicity of complex traits is explained by negative selection LJ O'Connor, AP Schoech, F Hormozdiari, S Gazal, N Patterson, AL Price The American Journal of Human Genetics 105 (3), 456-476, 2019 | 235 | 2019 |