Elucidation of distinct ligand binding sites for cytochrome P450 3A4 NA Hosea, GP Miller, FP Guengerich Biochemistry 39 (20), 5929-5939, 2000 | 289 | 2000 |
Modeling epoxidation of drug-like molecules with a deep machine learning network TB Hughes, GP Miller, SJ Swamidass ACS central science 1 (4), 168-180, 2015 | 199 | 2015 |
Characterization of human hepatic and extrahepatic UDP-glucuronosyltransferase enzymes involved in the metabolism of classic cannabinoids A Mazur, CF Lichti, PL Prather, AK Zielinska, SM Bratton, ... Drug Metabolism and Disposition 37 (7), 1496-1504, 2009 | 173 | 2009 |
Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants CH Yun, GP Miller, FP Guengerich Biochemistry 39 (37), 11319-11329, 2000 | 171 | 2000 |
Stretching exercises—flexibility in dihydrofolate reductase catalysis GP Miller, SJ Benkovic Chemistry & biology 5 (5), R105-R113, 1998 | 134 | 1998 |
Modeling reactivity to biological macromolecules with a deep multitask network TB Hughes, NL Dang, GP Miller, SJ Swamidass ACS central science 2 (8), 529-537, 2016 | 104 | 2016 |
Site of reactivity models predict molecular reactivity of diverse chemicals with glutathione TB Hughes, GP Miller, SJ Swamidass Chemical research in toxicology 28 (4), 797-809, 2015 | 98 | 2015 |
Vlbi aperture synthesis observations of the oh maser source w75 n AD Haschick, MJ Reid, BF Burke, JM Moran, G Miller Astrophysical Journal, Part 1, vol. 244, Feb. 15, 1981, p. 76-87. 244, 76-87, 1981 | 92 | 1981 |
Diversity in the oxidation of substrates by cytochrome P450 2D6: lack of an obligatory role of aspartate 301− substrate electrostatic bonding FP Guengerich, GP Miller, IH Hanna, MV Martin, S Léger, C Black, ... Biochemistry 41 (36), 11025-11034, 2002 | 91 | 2002 |
Deletion of a Highly Motional Residue Affects Formation of the Michaelis Complex for Escherichia coli Dihydrofolate Reductase GP Miller, SJ Benkovic Biochemistry 37 (18), 6327-6335, 1998 | 86 | 1998 |
Strength of an Interloop Hydrogen Bond Determines the Kinetic Pathway in Catalysis by Escherichia coli Dihydrofolate Reductase GP Miller, SJ Benkovic Biochemistry 37 (18), 6336-6342, 1998 | 84 | 1998 |
CYP2E1 substrate inhibition: Mechanistic interpretation through an effector site for monocyclic compounds SL Collom, RM Laddusaw, AM Burch, P Kuzmic, MD Perry, GP Miller Journal of Biological Chemistry 283 (6), 3487-3496, 2008 | 79 | 2008 |
Binding and oxidation of alkyl 4-nitrophenyl ethers by rabbit cytochrome P450 1A2: evidence for two binding sites GP Miller, FP Guengerich Biochemistry 40 (24), 7262-7272, 2001 | 74 | 2001 |
Interloop Contacts Modulate Ligand Cycling during Catalysis by Escherichia coli Dihydrofolate Reductase GP Miller, DC Wahnon, SJ Benkovic Biochemistry 40 (4), 867-875, 2001 | 73 | 2001 |
Oxidation of Methoxyphenethylamines by Cytochrome P450 2D6: ANALYSIS OF RATE-LIMITING STEPS* 210 FP Guengerich, GP Miller, IH Hanna, H Sato, MV Martin Journal of Biological Chemistry 277 (37), 33711-33719, 2002 | 71 | 2002 |
Assessing cytochrome P450 and UDP-glucuronosyltransferase contributions to warfarin metabolism in humans GP Miller, DR Jones, SZ Sullivan, A Mazur, SN Owen, NC Mitchell, ... Chemical research in toxicology 22 (7), 1239-1245, 2009 | 60 | 2009 |
Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases A Zielinska, CF Lichti, S Bratton, NC Mitchell, A Gallus-Zawada, VH Le, ... Journal of Pharmacology and Experimental Therapeutics 324 (1), 139-148, 2008 | 56 | 2008 |
Novel multi-mode ultra performance liquid chromatography–tandem mass spectrometry assay for profiling enantiomeric hydroxywarfarins and warfarin in human plasma DR Jones, G Boysen, GP Miller Journal of Chromatography B 879 (15-16), 1056-1062, 2011 | 54 | 2011 |
Hydroxywarfarin Metabolites Potently Inhibit CYP2C9 Metabolism of S-Warfarin DR Jones, SY Kim, M Guderyon, CH Yun, JH Moran, GP Miller Chemical research in toxicology 23 (5), 939-945, 2010 | 52 | 2010 |
Oxidation of phenethylamine derivatives by cytochrome P450 2D6: the issue of substrate protonation in binding and catalysis GP Miller, IH Hanna, Y Nishimura, FP Guengerich Biochemistry 40 (47), 14215-14223, 2001 | 46 | 2001 |