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Svasti Haricharan
Svasti Haricharan
Sanford Burnham Prebys Medical Discovery Institute
Dirección de correo verificada de sbpdiscovery.org
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STAT signaling in mammary gland differentiation, cell survival and tumorigenesis
S Haricharan, Y Li
Molecular and cellular endocrinology 382 (1), 560-569, 2014
1432014
Somatic mutation load of estrogen receptor-positive breast tumors predicts overall survival: an analysis of genome sequence data
S Haricharan, MN Bainbridge, P Scheet, PH Brown
Breast cancer research and treatment 146, 211-220, 2014
1192014
Functional annotation of ESR1 gene fusions in estrogen receptor-positive breast cancer
JT Lei, J Shao, J Zhang, M Iglesia, DW Chan, J Cao, M Anurag, P Singh, ...
Cell reports 24 (6), 1434-1444. e7, 2018
992018
Endocrine therapy resistance: new insights
JT Lei, M Anurag, S Haricharan, X Gou, MJ Ellis
The Breast 48, S26-S30, 2019
952019
TLR4 has a TP53-dependent dual role in regulating breast cancer cell growth
S Haricharan, P Brown
Proceedings of the National Academy of Sciences 112 (25), E3216-E3225, 2015
852015
Comprehensive profiling of DNA repair defects in breast cancer identifies a novel class of endocrine therapy resistance drivers
M Anurag, N Punturi, J Hoog, MN Bainbridge, MJ Ellis, S Haricharan
Clinical Cancer Research 24 (19), 4887-4899, 2018
792018
Loss of MutL disrupts CHK2-dependent cell-cycle control through CDK4/6 to promote intrinsic endocrine therapy resistance in primary breast cancer
S Haricharan, N Punturi, P Singh, KR Holloway, M Anurag, J Schmelz, ...
Cancer discovery 7 (10), 1168-1183, 2017
762017
Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation
JP Reddy, S Peddibhotla, W Bu, J Zhao, S Haricharan, YCN Du, ...
Proceedings of the National Academy of Sciences 107 (8), 3728-3733, 2010
592010
Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy
S Haricharan, J Dong, S Hein, JP Reddy, Z Du, M Toneff, K Holloway, ...
Elife 2, e00996, 2013
562013
Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast
G Liti, S Haricharan, FA Cubillos, AL Tierney, S Sharp, AA Bertuch, ...
PLoS genetics 5 (9), e1000659, 2009
542009
Ku must load directly onto the chromosome end in order to mediate its telomeric functions
CR Lopez, A Ribes-Zamora, SM Indiviglio, CL Williams, S Haricharan, ...
PLoS genetics 7 (8), e1002233, 2011
512011
Luminal epithelial cells within the mammary gland can produce basal cells upon oncogenic stress
SM Hein, S Haricharan, AN Johnston, MJ Toneff, JP Reddy, J Dong, W Bu, ...
Oncogene 35 (11), 1461-1467, 2016
442016
DNA damage repair defects as a new class of endocrine treatment resistance driver
M Anurag, MJ Ellis, S Haricharan
Oncotarget 9 (91), 36252, 2018
422018
RETRACTED ARTICLE: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma
A Garancher, H Suzuki, S Haricharan, LQ Chau, MB Masihi, JM Rusert, ...
Nature neuroscience 23 (7), 842-853, 2020
372020
Mismatch repair-deficient hormone receptor-positive breast cancers: Biology and pathological characterization
E Sajjadi, K Venetis, R Piciotti, M Invernizzi, E Guerini-Rocco, ...
Cancer Cell International 21, 1-10, 2021
322021
Mismatch repair testing in breast cancer: the path to tumor-specific immuno-oncology biomarkers
K Venetis, E Sajjadi, S Haricharan, N Fusco
Translational Cancer Research 9 (7), 4060, 2020
312020
CDK4/6 inhibitor biomarker research: are we barking up the wrong tree?
M Anurag, S Haricharan, MJ Ellis
Clinical Cancer Research 26 (1), 3-5, 2020
232020
Contribution of an alveolar cell of origin to the high-grade malignant phenotype of pregnancy-associated breast cancer
S Haricharan, SM Hein, J Dong, MJ Toneff, OH Aina, PH Rao, RD Cardiff, ...
Oncogene 33 (50), 5729-5739, 2014
192014
HER2 activation and endocrine treatment resistance in HER2-negative breast cancer
A Mazumder, S Shiao, S Haricharan
Endocrinology 162 (10), bqab153, 2021
172021
Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer
NB Punturi, S Seker, V Devarakonda, A Mazumder, R Kalra, CH Chen, ...
Nature communications 12 (1), 2940, 2021
172021
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